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Growth hormone levels in psoriasis

Summary

Plasma growth-hormone levels in 12 fasting psoriatics were 4.4±1.4 mU/l (mean±SEM), compared to 2.7±1.7 in 5 patients with eczema and 1.2±0.3 in 6 normal subjects. The differences in mean values were not statistically significant and were due to exceptionally high levels of growth hormone in five patients with psoriasis and one patient with eczema. In the psoriatic group the exceptional patients were not distinguished by age or the area of involved skin but they tended to be leaner than those with low plasma-growth hormone levels. We conclude that raised plasma growth hormone cannot be the cause of psoriasis but might be a secondary effect of the skin disease in some patients.

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References

  1. 1.

    Franks S (1979) Prolactin. In: Gray CH, James VHT (eds) Hormones in blood, vol 1. Academic Press, New York, pp 280–331

  2. 2.

    Glinski IN, Zarebska Z, Jablonska S, Imiela J, Nosarzewski J (1980) The activity of polymorphonuclear leucocyte neutral proteinases and their inhibitors in patients with psoriasis treated with a continuous peritoneal dialysis. J Invest Dermatol 75: 481–487

  3. 3.

    Holzmann H, Eissner D, Hahn K, Thiers G, Böhm G (1982) The psoriatic bone manifestation. In: Farber EM, Cox AJ (eds) Psoriasis. Proceedings of the Third International Symposium. Grune and Stratton, New York, pp 335–336

  4. 4.

    Hopsu-Havu VK, Terho PE, Vanha-Perttula TP, Vilganen MK (1973) Response of blood insulin and growth hormone to glucose infusion in normal, psoriatic and diabetic persons. Acta Derm Venereol (Stockholm) 53:39–44

  5. 5.

    Hopsu-Havu VK, Niinikoski A, Haapalahti JE, Jansen CT (1973) Serum insulin and growth hormone response to arginine infusion in healthy and psoriatic persons. Dermatologica 146:205–210

  6. 6.

    Hunter WM (1976) Growth hormone. In: Lorraine JA, Bell ET (eds) Hormone assays and their application, 4th edn. Churchill Livingstone, Edinburgh, pp 221–284

  7. 7.

    Hunter WM (1976) Radioimmunoassay of growth hormone (HGH) in plasma. In: Bruer H, Hamel D, Kruskemper HC (eds) Methods of hormone analysis. Georg Thieme, Stuttgart; Wylie, New York, pp 1–11

  8. 8.

    Hwang P, Guyda H, Friesen H (1971) A radioimmunoassay for human prolactin. Proc Natl Acad Sci USA 68:1902–1906

  9. 9.

    Kreuger GG (1981) Psoriasis. In: Dobson RL, Thiers BH (eds) Yearbook of dermatology. Yearbook Medical Publishers, Chicago, pp 13–70

  10. 10.

    MacKie RM, Beastall GM, Thomson JA (1983) Growth hormone levels in psoriasis. Arch Dermatol Res 275:207

  11. 11.

    Namey TC, Rosenthal L (1976) Periarticular uptake of 99m-technetium diphosphonate in psoriatics: correlation with cutaneous activity. Arthritis Rheum 19:607–612

  12. 12.

    Weber G, Neidhardt M, Schmidt A, Geiger A (1981) The correlation of growth hormone and clinical picture in psoriasis. Arch Dermatol Res 270:129–140

  13. 13.

    Weber G, Klughardt G, Niedhardt M (1981) Psoriasis and human growth hormone: aetiology and therapy. Arch Dermatol Res 270:361–365

  14. 14.

    Weber G, Neidhardt M, Frey H, Galle K, Geiger A (1981) Treatment of psoriasis with bromocriptin. Arch Dermatol Res 271:437–439

  15. 15.

    Weber G, Klughardt G, Neidhardt M, Galle R, Frey H, Geiger A (1982) Treatment of psoriasis with somatostatin. Arch Dermatol Res 272:31–36

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Correspondence to G. C. Priestley.

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Priestley, G.C., Gawkrodger, D.J., Seth, J. et al. Growth hormone levels in psoriasis. Arch Dermatol Res 276, 147–150 (1984). https://doi.org/10.1007/BF00414010

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Key words

  • Psoriasis
  • Growth hormone