Archives of Dermatological Research

, Volume 281, Issue 8, pp 538–540 | Cite as

Histological defects of chronic benign familial pemphigus expressed in tissue culture

  • M. Regnier
  • J -P Ortonne
  • M. Darmon
Short Communications

Key words

Hailey-Hailey disease Reconstructed epidermis Dermis phenotype Pemphigus 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Asselineau D, Bernard BA, Bailly C, Darmon M (1985) Epidermal morphogenesis and induction of the 67K, keratin polypeptide by culture of human keratinocytes at the air-liquid interface. Exp Cell Biol 159:536–539Google Scholar
  2. 2.
    Asselineau D, Bernard BA, Bailly C, Darmon M, Prunieras M (1986) Human epidermis reconstructed by culture: Is it “normal”? J Invest Dermatol 86:181–186Google Scholar
  3. 3.
    Boukamp P, Rupniak HTR, Fusenig NE (1985) Environmental modulation of expression of differentiation and malignancy in six human squamous cell carcinoma cell lines. Cancer Res 45:5582–5592Google Scholar
  4. 4.
    De Dobbeleer G, de Graeve C, Gourdain JM, Heenen M (1988) Reproduction of the characteristic morphologic changes of familial benign chronic pemphigus (FBCP) in cultures of lesional keratinocytes onto healthy heterologous dead deepidermized dermis (D.E.D.). J Invest Dermatol 91: 415AGoogle Scholar
  5. 5.
    Fleckman P, Sybert VP, Dale BA, Holbrook KA (1985) Cultured human keratinocytes from patients with ichthyosis vulgaris are phenotypically abnormal. Clin Res 33: 637AGoogle Scholar
  6. 6.
    Fuchs E, Green H (1980) Changes in keratin gene expression during terminal differentiation of the keratinocyte. Cell 19:1033–1042Google Scholar
  7. 7.
    Green H, Watt FM (1982) Regulation by vitamin A of envelope cross-linking in cultured keratinocytes derived from different human epithelia. Mol Cell Biol 2:1115–1117Google Scholar
  8. 8.
    Green H, Kehinde O, Thomas J (1979) Growth of cultured human epidermal cells into multiple epithelia suitable for grafting. Proc Natl Acad Sci USA 76:5665–5668Google Scholar
  9. 9.
    Haber H, Russell LB (1950) Sisters with familial benign chronic pemphigus (Gougerot, Hailey and Hailey). Br J Dermatol 62:458–460Google Scholar
  10. 10.
    Hill HW, Mackenzie IC (1984) The influence of differing connective tissue substrates on the maintenance of adult stratified squamous epithelia. Cell Tissue Res 237:473–478Google Scholar
  11. 11.
    Kim KH, Schwartz F, Fuchs E (1984) Differences in keratin synthesis between normal epithelial cells and squamous cell carcinomas are mediated by vitamin A. Proc Natl Acad Sci (USA) 81:4280–4284Google Scholar
  12. 12.
    Kubilus J, Rand R, Baden HP (1981) Effects of retinoic acid and other retinoids on the growth and differentiation of 3T3 supported human keratinocytes. In Vitro 17:786–795Google Scholar
  13. 13.
    Mackenzie IC, Hill MW (1984) Connective tissue influences on patterns of epithelial architecture and keratinization in skin and oral mucosa of the adult mouse. Cell Tissue Res 235:551–559Google Scholar
  14. 14.
    McCance DJ, Kopan R, Fuchs E, Laimins LA (1988) Human papillomavirus type 16 alters human epithelial cell differentiation in vitro. Proc Natl Acad Sci USA 85:7169–7173Google Scholar
  15. 15.
    Prunieras M, Regnier M, Woodley D (1983) Methods of cultivation of keratinocytes with an air-liquid interface. J Invest Dermatol 81:28s-33sGoogle Scholar
  16. 16.
    Regnier M, Prunieras M, Woodley D (1981) Growth and differentiation of adult human epidermal cells on dermal substrates. Front Matrix Biol 9:4–35Google Scholar
  17. 17.
    Regnier M, Schweizer J, Michel S, Bailly C, Prunieras M (1986) Expression of high molecular weight (67K) keratin in human keratinocytes cultured on dead de-epidermized dermis. Exp Cell Res 165:63–72Google Scholar
  18. 18.
    Regnier M, Desbas C, Bailly C, Darmon M (1988) Differentiation of normal and tumoral human keratinocytes cultured on dermis: reconstruction of either normal or tumoral architecture. In Vitro 24:625–632Google Scholar
  19. 19.
    Rheinwald JG, Green H (1975) Serial cultivation of strains of human keratinocytes: the formation of keratinizing colonies from single cells. Cell 6:331–343Google Scholar
  20. 20.
    Vermorken AJM (1985) Culture techniques and potential research applications of human hair follicle cells in vitro. ATLA 13:8–37Google Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • M. Regnier
    • 1
  • J -P Ortonne
    • 2
  • M. Darmon
    • 1
  1. 1.Centre International de Recherches DermatologiquesValbonneFrance
  2. 2.Service de DermatologieHôpital PasteurNiceFrance
  3. 3.Cell Biology DepartmentC.I.R.D.Valbonne CédexFrance

Personalised recommendations