A study on the candida-killing activity of polymorphonuclear leukocytes in patients with psoriasis vulgaris
The Candida albicans killing capacity, a function of polymorphonuclear leukocytes from patients with psoriasis vulgaris was significantly higher than that of granulocytes from healthy persons. This observation is a further data supporting the concept of the “activated granulocyte” in psoriasis.
Key wordGranulocyte Candida killing Psoriasis
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- 1.Breathnach SM, Carrington P, Black MM (1981) Neutrophil leukocyte migration in psoriasis vulgaris. J Invest Dermatol 76:271–275Google Scholar
- 2.Cotterill JA, Roberts MM, Freeman R, Mostoufi K (1974) Aspects of polymorph function in psoriasis. Proc Royal Soc Med 67:874–875Google Scholar
- 3.Csató M, Dobozy A, Simon N (1980) Study of phagocytic function with a quantitative nitrobluetetrazolium (NBT) reduction test in diabetes mellitus. Arch Dermatol Res 268:283–288Google Scholar
- 4.Csató M, Hunyadi J, Dobozy A, Kenderessy SzA, Simon N (1981) Polymorphonuclear granulocyte chemotaxis and chemotactic factor generation by Concanavalin A-stimulated peripheral blood mononuclear cells in patients with psoriasis. Arch Dermatol Res Submitted for publicationGoogle Scholar
- 5.Kawohl G, Szperalski B, Schröder JM, Christophers E (1980) Polymorphonuclear leukocyte chemotaxis in psoriasis: enhancement by self-activated serum. Br J Dermatol 103:527–535Google Scholar
- 6.Lehrer RI, Cline MJ (1969) Interaction of Candida albicans with human leukocytes and serum. J Bacteriol 98:996–1004Google Scholar
- 7.Michaälsson G (1980) Increased chemotatic activity of neutrophil leukocytes in psoriasis. Br J Dermatol 103:351–357Google Scholar
- 8.Rosling AE, Rhodes EI, Watson B, Williams B (1978) Neutrophil function in some skin diseases using zymosan as a stimulus in the nitroblue-tetrazolium test. Clin Exp Dermatol 3:429–435Google Scholar
- 9.Sedgwick JB, Bergstresser PR, Hurd ER (1980) Increased granulocyte adherence in psoriasis and psoriatic arthritis. J Invest Dermatol 74:81–84Google Scholar
- 10.Sedgwick JB, Bergstresser PR, Hurd ER (1981) Increased superoxide generation by normal granulocytes incubated in sera from patients with psoriasis. J Invest Dermatol 76:158–164Google Scholar
- 11.Silny W, Pehamberger H, Zielinsky C, Gschnait F (1980) Effect of PUVA treatment on the locomotion of polymorphonuclear leukocytes and mononuclear cells in psoriasis. J Invest Dermatol 75:187–188Google Scholar
- 12.Wahba A, Cohen HA, Bar-Eli M, Gallily R (1978) Enhanced chemotactic and phagocytic activities of leukocytes in psoriasis vulgaris. J Invest Dermatol 71:186–188Google Scholar