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Ultra-violet induced mutations to growth factor requirement and penicillin resistance in a blue-green alga

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After exposures to UV, two mutant strains of Phormidium mucicola were isolated which are stable and inheritable:

1. Strain 5/5 mL-1 is a photoheterotrophic mutant requiring addition of an organic growth factor to the basal medium which appears fulfilled by either casein hydrolysate, glucose, acetate or vitamin mixture and fails to grow heterotrophically.

2. mr/p. This strain shows resistance upto 10.24 μg/ml of penicillin whereas the parent does not survive beyond a penicillin dose of 0.1 μg/ml.

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Srivastava, B.S. Ultra-violet induced mutations to growth factor requirement and penicillin resistance in a blue-green alga. Archiv. Mikrobiol. 66, 234–238 (1969). https://doi.org/10.1007/BF00412055

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  • Glucose
  • Acetate
  • Growth Factor
  • Penicillin
  • Basal Medium