Studies of the influences of pregnancy and lactation on the thymus in the mouse

  • Takashi Ito
  • Takeshi Hoshino
Article

DOI: 10.1007/BF00410229

Cite this article as:
Ito, T. & Hoshino, T. Z.Zellforsch (1962) 57: 667. doi:10.1007/BF00410229

Summary

Influences of pregnancy and lactation on the thymus were quantitatively and microscopically studied in the mouse. Thytnic involution due to pregnancy occurs in later pregnancy and reaches a maximum at parturition. After parturition the involuted thymus regenerates, but lactation has an inhibitory influence on the regeneration. The possible significance of the thymic changes is discussed particularly in relation to the adrenocortical activity. Histologically the cortex exhibits prominent alterations during the involution and regeneration. The pattern of depletion and repopulation of lymphocytes in the cortex is similar to that in other types of acute involution. The medulla also undergoes microscopic changes which are revealed particularly by the histometric examination of its components.

Copyright information

© Springer-Verlag 1962

Authors and Affiliations

  • Takashi Ito
    • 1
  • Takeshi Hoshino
    • 1
  1. 1.Department of AnatomyHokkaido University School of MedicineSapporoJapan

Personalised recommendations