Clinical prediction of insightful response to a single large dose of LSD
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Twenty psychiatric inpatients were given a single 2.5 mcg/kg intravenous dose of LSD in the context of a prolonged interview session after preliminary clinical study and indoctrination. Insightful responses, as rated from tape recordings, were found more frequently in patients with characteristics of psychopathic personality than in other types of patients. No responders were less than 22 years of age. A attempt to use methamphetamine as a comparison drug showed that it was easily distinguishable from LSD by clinical observation, Jarvik Questionnaire and Bender-Gestalt score changes, and from randomly selected brief samples of tape recorded verbalization.
KeywordsClinical Study Clinical Observation Large Dose Methamphetamine Score Change
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