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Vascularization and curability of stage III and IV nasopharyngeal tumors

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In a retrospective study the capillary density was determined in biopsies from 25 cases of nasopharyngeal tumor, stages III and IV. Determinations were made on stained histological sections by counting the capillaries within a standard field size and at standard magnification. A statistically significant correlation was found to exist between capillary density and survival time of patients treated with radiotherapy and eventually with chemotherapy. No correlation between survival and age or sex of the patients, or stage of tumor, was noted. It is concluded that capillary density in nasopharyngeal tumors has a predictive value.

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  1. Awwad HK, El Naggar M, Mocktar N, Barsoum M (1986) Intercapillary distance measurement as an indicator of hypoxia in carcinoma of the cervix uteri. Int J Radiat Oncol Biol Phys 12:1329–1333

  2. Brady LW (ed) (1980) Radiation sensitizers. Masson, New York

  3. Fletcher GH (1975) Textbook of radiotherapy, 2nd ed. Lea & Febiger, Philadelphia

  4. Kolstad P (1968) Vascularization, oxygen tension and local recurrence in cervix cancer. Scand J Clin Lab Invest 106 (Suppl): 145–157

  5. Price LA, Hill BT (1977) Kinetically-based logical approach to the tumor therapy of head and neck cancer. Clin Otolaryngol 2:339–345

  6. Siracka E, Siracky J, Pappova N, Révész L (1982) Vascularization and radiocurability in cancer of the uterine cervix. Neoplasma 29:183–188

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Correspondence to G. S. Delides.

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Delides, G.S., Venizelos, J. & Révész, L. Vascularization and curability of stage III and IV nasopharyngeal tumors. J Cancer Res Clin Oncol 114, 321–323 (1988).

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Key words

  • Nasopharyngeal tumors
  • Tumor vascularization
  • Oxygen effect