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Light and electron microscopy of Sondermann's channels in the human trabecular meshwork

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Channels identified as Sondermann's “inner canaliculi” were found in the trabecular meshwork of both infant and adult eyes of the human by means of light and electron microscopy. They were lined by endothelia, and were located in the endothelial meshwork. They clearly opened into Schlemm's canal. The structure of these channels has been described. Conclusive information, with respect to the relation of these channels to the intertrabecular spaces and, therefore, the anterior chamber, has not been obtained. However, study of serial electron micrographs strongly suggests that the channels communicated with such spaces.

Light microscopy of this area showed that the channels had a complicated course, and that some of them were more slit-like in cross section than tubules.


Im Trabekelwerk menschlicher Augen wurden licht- und elektronenmikroskopisch Kanälchen nachgewiesen, die als Sondermannsche Innenkanälchen identifiziert werden konnten. Sie sind mit Endothel ausgekleidet, befinden sich im Trabeculum cribriforme und weisen eine Öffnung zum Schlemmschen Kanal auf. Die Feinstruktur dieser Kanälchen wird beschrieben. Bisher konnte jedoch nicht endgültig abgeklärt werden, ob diese Kanälchen mit den intertrabekulären Zwischenräumen in Beziehung stehen und damit auch mit der Vorderkammer verbunden sind. Elektronenmikroskopische Serienuntersuchungen lassen jedoch vermuten, daß diese Kanälchen mit den genannten Zwischenräumen in direkter Verbindung stehen.

Lichtmikroskopische Untersuchungen dieses Gebietes zeigen, daß diese Kanälchen einen komplizierten Verlauf nehmen und daß einige von ihnen im Querschnitt eher schlitzförmig als röhrenförmig aussehen.

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This investigation was conducted under a Fight for Sight Postdoctoral Research Fellowship of the National Council to Combat Blindness, Inc., New York, N.Y.

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Iwamoto, T. Light and electron microscopy of Sondermann's channels in the human trabecular meshwork. Albrecht von Graefes Arch. Klin. Ophthalmol. 172, 197–212 (1967).

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