, Volume 6, Issue 3, pp 229–233 | Cite as

A comparison of 2,3-dihydro-lysergic acid diethylamide with LSD-25

  • Charles W. Gorodetzky
  • Harris Isbell
Original Investigations


  1. 1.

    The 2,3-dihydro-diethylamide of lysergic acid induces LSD-like autonomic and mental changes in man but is less potent than LSD.

  2. 2.

    The effects of 2,3-DH-LSD appear more slowly than those of LSD-25.

  3. 3.

    The low potency (relative to LSD-25) of 2,3-DH-LSD in inducing fever in rabbits correlates with a relatively low potency in inducing autonomic and psychotomimetic effects in man.



Mental Change Lysergic Acid Diethylamide Psychotomimetic Effect 
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Copyright information

© Springer-Verlag 1964

Authors and Affiliations

  • Charles W. Gorodetzky
    • 1
    • 2
  • Harris Isbell
    • 1
    • 2
  1. 1.U.S. Department of Health, Education and Welfare, Public Health ServiceNational Institute of Mental Health, Addiction Research Center, PHS HospitalLexingtonUSA
  2. 2.Department of MedicineUniversity of Kentucky College of MedicineLexingtonUSA

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