, Volume 38, Issue 9, pp 1061–1068

Diabetes as a risk factor for stroke. A population perspective

  • B. Stegmayr
  • K. Asplund


Stroke incidence, case fatality and mortality in diabetic patients were compared to non-diabetic subjects in a 35–74-year-old population in northern Sweden (target population 241,000). During an 8-year period, 1,544 stroke events in diabetic patients and 4,826 events in non-diabetic subjects were recorded. The crude incidence of stroke was 1,000 per 100,000 in the diabetic men vs 247 in the non-diabetic men (relative risk 4.1; 95% confidence interval 3.2–5.2). Among diabetic women, the crude incidence was 757 per 100,000 and 152 in non-diabetic women (relative risk 5.8; 95% confidence interval 3.7–6.9). The 28-day case fatality among men was similar in the diabetic and non-diabetic stroke patients (18.6 vs 17.1%; p=0.311), but significantly higher in diabetic women compared with non-diabetic women (22.2 vs 17.9%; p=0.02). When compared with the non-diabetic population, the overall mortality from stroke in the diabetic population (first and recurrent) was 4.4-times higher in male and 5.1-times higher in the female patients. Hypertension, atrial fibrillation, heart failure or myocardial infarction were all significantly more common in diabetic than in non-diabetic stroke patients. The population attributable risk, a crude estimate of all strokes ascribed to diabetes mellitus, was 18% in men and 22% in women. In Sweden, about 50 strokes are annually directly attributed to diabetes in a population of 100,000 in this age group.

Key words

Diabetes mellitus cerebrovascular disorders case fatality stroke mortality stroke incidence epidemiology WHO MONICA population attributable risk Sweden 



Multinational Monitoring of Trends and Determinants in Cardiovascular Disease


International Classification of Diseases


computerised tomography


confidence interval


relative risk


case fatality


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Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • B. Stegmayr
    • 1
  • K. Asplund
    • 1
  1. 1.Department of MedicineUniversity HospitalUmeåSweden

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