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Esterase D polymorphism in a French-Canadian population

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Summary

Red blood cell esterase D (ESD) polymorphism was studied in a French-Canadian population from Quebec city, Canada, by means of high voltage electrophoresis on agarose gel followed, in heterozygotes for ESD1, by IEF to reveal the possible allele ESD*5. Frequencies of the ESD alleles in 904 unrelated individuals were ESD*1: 0.888, EDS*2: 0.095 and ESD*5: 0.017. The segregation pattern observed in 275 families confirmed a Mendelian inheritance of three autosomal alleles.

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References

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Correspondence to C. Bouchard.

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Couture, L., Chagnon, M., Allard, C. et al. Esterase D polymorphism in a French-Canadian population. Hum Genet 73, 276 (1986). https://doi.org/10.1007/BF00401244

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Keywords

  • Internal Medicine
  • Blood Cell
  • Agarose
  • Metabolic Disease
  • High Voltage