Red blood cell esterase D (ESD) polymorphism was studied in a French-Canadian population from Quebec city, Canada, by means of high voltage electrophoresis on agarose gel followed, in heterozygotes for ESD1, by IEF to reveal the possible allele ESD*5. Frequencies of the ESD alleles in 904 unrelated individuals were ESD*1: 0.888, EDS*2: 0.095 and ESD*5: 0.017. The segregation pattern observed in 275 families confirmed a Mendelian inheritance of three autosomal alleles.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Changnon YC, Bouchard C, Allard C (1981) Isoelectric focusing of red cell phosphoglucomutase (E. C.: 184.108.40.206.) at the PGM locus in a French Canadian population. Hum Genet 59:36–38
Dykes DD, Polesky HF, Miller S (1982) Frequency of the ESD 5 allele in three ethnic groups in Minnesota. Hum Genet 62:162–163
Koster B, Leupold H, Mauff G (1975) Esterase D polymorphism: high-voltage agarose-gel electrophoresis and distribution of phenotypes in different European populations. Humangenetik 28:75–78
Nishigaki I, Itoh T (1984) Isoelectric focusing studies of human red cell esterase D: evidence for polymorphic occurrence of a allele ESD 7 in Japanese. Hum Genet 66:92–95
Radola BJ (1980) Ultrathin-layer isoelectric focusing in 50–100 μm polyacrylamide gels on silanized glass plates or polyester films. In: Radola BJ (ed) Electrophoresis 79. de Gruyter, Berlin, pp 79–94
About this article
Cite this article
Couture, L., Chagnon, M., Allard, C. et al. Esterase D polymorphism in a French-Canadian population. Hum Genet 73, 276 (1986). https://doi.org/10.1007/BF00401244
- Internal Medicine
- Blood Cell
- Metabolic Disease
- High Voltage