, Volume 84, Issue 2, pp 159–171 | Cite as

Histone genes are located at the sphere loci of newt lampbrush chromosomes

  • Joseph G. Gall
  • Edwin C. Stephenson
  • Harry P. Erba
  • Manuel O. Diaz
  • Giuseppina Barsacchi-Pilone


In situ hybridization experiments on mitotic and lampbrush chromosomes show that histone genes and an associated 222 bp repeated sequence, satellite 1, are located at or near the sphere loci of chromosomes 2 and 6 of the newt Notophthalmus viridescens. During the lampbrush chromosome stage, transcripts of the histone genes and of satellite 1 occur on loops associated with the spheres. Histone genes are located at sites on the mitotic chromosomes of Triturus cristatus and T. alpestris which are consistent with the known positions of spheres on their lampbrush chromosomes.


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Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • Joseph G. Gall
    • 1
  • Edwin C. Stephenson
    • 1
  • Harry P. Erba
    • 1
  • Manuel O. Diaz
    • 1
  • Giuseppina Barsacchi-Pilone
    • 1
    • 3
  1. 1.Department of BiologyYale UniversityNew HavenUSA
  2. 2.Department of BiologyIndiana UniversityBloomingtonUSA
  3. 3.Istituto di Istologia e EmbriologiaUniversita degli studi di PisaPisaItaly

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