The influence of substances extracted from cigarette-smoke on mitotic processes in Allium cepa
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The influence of solutions of cigarettetar, from which the carcinogenic polycyclic hydrocarbons have been removed, upon the mitotic processes in roottips of Allium cepa, was studied.
These solutions changed the mitotic picture, in such a way that the prophases decreased, the telophases increased.
Under influence of these solutions the nuclear divisions became abnormal. The abnormalities included disturbances of the spindlefigure. fragmentations and overspiralization of the chromosomes.
These solutions seemed to have disturbed synthesis of proteins.
In the discussion an effort has been made to relate these disturbances to disturbances of synthesis of RNA.
It is still uncertain what influence these solutions have after intraperitoneal injection into mice.
KeywordsNuclear Membrane Interphase Nucleus Nuclear Division CEPA Acid Fuchsin
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- Blacklock, J. W. S.: See: International Cancer Congress. Science 128, 1513 (1958).Google Scholar
- Kaufmann, B. P., and N. K. Das: Induction of mitotic abnormalities by ribonuclease. Carnegie Inst. Yearbook 52, 238 (1953).Google Scholar
- Lasnitzky, I.: The effect of carcinogens, hormones and vitamins on organ cultures. Int. Rev. Cytol. 7, 80–118 (1958).Google Scholar
- -, and E. L. Kennaway: Report Strangeways Research Laboratory. 1955, 22. Cited after Lasnitzky.Google Scholar
- Peacock, P. R.: See: International Cancer Congress. Science 128, 1513 (1958).Google Scholar