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Chromosoma

, Volume 10, Issue 1–6, pp 679–685 | Cite as

The influence of substances extracted from cigarette-smoke on mitotic processes in Allium cepa

  • G. Venema
Article

Summary

  1. 1.

    The influence of solutions of cigarettetar, from which the carcinogenic polycyclic hydrocarbons have been removed, upon the mitotic processes in roottips of Allium cepa, was studied.

     
  2. 2.

    These solutions changed the mitotic picture, in such a way that the prophases decreased, the telophases increased.

     
  3. 3.

    Under influence of these solutions the nuclear divisions became abnormal. The abnormalities included disturbances of the spindlefigure. fragmentations and overspiralization of the chromosomes.

     
  4. 4.

    These solutions seemed to have disturbed synthesis of proteins.

     
  5. 5.

    In the discussion an effort has been made to relate these disturbances to disturbances of synthesis of RNA.

     
  6. 6.

    It is still uncertain what influence these solutions have after intraperitoneal injection into mice.

     

Keywords

Nuclear Membrane Interphase Nucleus Nuclear Division CEPA Acid Fuchsin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Blacklock, J. W. S.: See: International Cancer Congress. Science 128, 1513 (1958).Google Scholar
  2. Brachet, J.: Effects of ribonuclease on the metabolism of living root-tip cells. Nature (Lond.) 174, 876–877 (1954).CrossRefGoogle Scholar
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  9. Peacock, P. R.: See: International Cancer Congress. Science 128, 1513 (1958).Google Scholar

Copyright information

© Springer-Verlag 1959

Authors and Affiliations

  • G. Venema
    • 1
  1. 1.Genetical InstituteGovernment University GroningenThe Netherlands

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