Human Genetics

, Volume 43, Issue 1, pp 115–117 | Cite as

15/17 Translocation in acute promyelocytic leukaemia

  • J. M. J. C. Scheres
  • T. W. J. Hustinx
  • G. A. M. de Vaan
  • F. J. Rutten
Clinical Case Reports
Received:

Summary

A translocation between a chromosome 15 and a chromosome 17 was found in the bone marrow of a 14-year-old boy who had clinical and laboratory symptoms of acute promyelocytic leukemia (APL). As far as we know, this is the sixth case of APL with 15/17 translocation to be reported in the literature. This observation gives further support to the hypothesis that there is an association between this chromosomal rearrangement and APL.

Keywords

Bone Marrow Internal Medicine Leukemia Metabolic Disease Acute Promyelocytic Leukemia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • J. M. J. C. Scheres
    • 1
  • T. W. J. Hustinx
    • 1
  • G. A. M. de Vaan
    • 2
  • F. J. Rutten
    • 1
  1. 1.Department of Human Genetics, Division of CytogeneticsUniversity of NijmegenThe Netherlands
  2. 2.Department of Pediatrics, Oncology Unit, Faculty of MedicineUniversity of NijmegenThe Netherlands

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