The multiplication of Escherichia coli C containing either the plasmid R46 or its non-selftransmissible derivative was studied in the presence or absence of the isogenic R− parent strain. Neither plasmid conferred any detectable effect on the host's ability to multiply. Similarly under conditions of prolonged incubation neither plasmid conferred a disadvantage on its host when the bacteria were grown in pure culture. However, when the incubation of mixed R+/R− cultures was prolonged, the possession of either R-plasmid resulted in small but reproducible differences which favoured the R− strain.
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Alldrick, A.J., Smith, J.T. R-plasmid effects on bacterial multiplication and survival. Antonie van Leeuwenhoek 49, 133–142 (1983). https://doi.org/10.1007/BF00393671
- Escherichia Coli
- Pure Culture
- Parent Strain
- Detectable Effect
- Bacterial Multiplication