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Translocation D/D involving two homologous chromosomes of the pair 15

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A translocation between two homologues of chromosomes 15 was identified in a phenotypically normal female with the R-banding technique. The C-banding technique demonstrated an abnormally large band on the translocation chromosome. This finding suggests a possibility that the translocation might be due to breaks in the short arms or to fusion at telomeric ends. The patient had four spontaneous abortions and no normal pregnancy.

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Žižka, J., Balíĉek, P. & Finková, A. Translocation D/D involving two homologous chromosomes of the pair 15. Hum Genet 36, 123–125 (1977). https://doi.org/10.1007/BF00390444

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  • Internal Medicine
  • Metabolic Disease
  • Spontaneous Abortion
  • Homologous Chromosome
  • Normal Pregnancy