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Replacement of epiphyseal bone with methylmethacrylate: Its effect on articular cartilage

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Summary

Methylmethacrylate cement was used as a substitute for the epiphyseal bone of the canine proximal femora, after femoral neck osteotomy. The effects of different volumes of acrylic cement on the integrity of trabecular bone and articular cartilage and the effects of different types of fixation of the osteotomy site were assessed clinically, radiologically and histologically. Degenerative changes occurring in the articular cartilage were greatest when a large area of epiphyseal bone was replaced with methylmethacrylate. These degenerative changes varied proportionately with the rigidity of fixation at the osteotomy site. Rigid fixation resulted in a better clinical and radiographic assessment and a decrease in histopathologic changes in the articular cartilage.

Zusammenfassung

Methakrylat-Zement wurde als Ersatz für die proximale Femurepiphyse beim Hund nach Schenkelhalsosteotomie verwendet. Die Auswirkungen verschiedener Mengen des MethakrylatZements auf die Unversehrtheit der trabekulären Knochenstruktur und des Gelenkknorpels und der Effekt der verschiedenen Arten der Fixation der Ostetomie wurden klinisch, radiographisch and histologisch untersucht. Die stärksten degenerativen Veränderungen in dem Gelenkknorpel wurden beobachtet, wenn ein ausgedehnter Bereich der Epiphyse durch Methakrylat ersetzt wurde. Diese degenerativen Veränderungen variierten proportional zu der Starrheit der Osteosynthese an der Osteotomiestelle. Eine starre Fixation ergab eine bessere klinische und radiographische Beurteilung der Knochenstruktur und geringere histologische Veränderungen des Gelenkknorpels.

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References

  1. 1.

    Barnes R, Brown JT, Garden RS, Nicholl EA (1976) Subcapital fractures of the femur. J Bone Jt Surg 58-B:2–24

  2. 2.

    Cameron HU, Jacob R, MacNab I, Pilliar RM (1975) Use of polymethylethacrylate to enhance screw fixation in bone. J Bone Jt Surg 57-A:655–656

  3. 3.

    Carlson DH (1974) The use of methylmethacrylate in repair of neoplastic lesions in bone. Radiol 112:43–46

  4. 4.

    Charnley J (1973) The reaction of bone to self curing acrylic cement. A long term histological study in man. J Bone Jt Surg 52-B:340–353

  5. 5.

    Daly WR (1979) Femoral head and neck fractures in the dog and cat. A review of 115 cases. Vet Surg 7:29–38

  6. 6.

    Enis JE, McCollough NC, Cooper JS (1974) Effects of methylmethacrylate in osteosynthesis. Clin Orthop 105:283–294

  7. 7.

    Glimcher MJ, Kenzora JE (1979) The biology of osteonecrosis of the human femoral head and its clinical implications. 1. Tissue biology. Clin Orthop 138:284–309

  8. 8.

    Glimcher MJ, Kenzora JE (1979) The biology of osteonecrosis of the human femoral head and its clinical implications. III. Discussion of the etiology and genesis of the pathological sequelae; comments on treatment. Clin Orthop 140:273–312

  9. 9.

    Harrington KD (1975) The use of methylmethacrylate as an adjunct in internal fixation of unstable, comminuted, intertrochanteric fractures in osteoporotic patients. J Bone Jt Surg 57-A:744–750

  10. 10.

    Hubbard MJS (1980) The effect of acrylic cement on the union of internally fixed experimental fractures of the femoral shaft in the rabbit. Injury 11:325–330

  11. 11.

    Hunter GA (1969) A comparison of the use of internal fixation and prosthetic replacement for fresh fractures of the neck of the femur. Br J Surg 56:229–232

  12. 12.

    Jensen TM, Dillon WL, Reckling FW (1976) Changing concepts in the management of pathological and impending pathological fractures. J Trauma 16:496–502

  13. 13.

    Kennedy WR (1978) Fractures of the tibial condyles: A preliminary report on supplementary fixation with methylmethacrylate. Clin Orthop 134:153–157

  14. 14.

    Linder L (1977) Reaction of bone to the acute chemical trauma of bone cement. J Bone Jt Surg 59-A: 82–86

  15. 15.

    Nunamaker DM (1973) Repair of femoral head and neck fractures by interfragmentary compression. J Am Vet Med Ass 162:569–572

  16. 16.

    Piermattei DL, Greeley RG (1979) Surgical approaches to the bones. 2nd ed. W. B. Saunders, Philadelphia

  17. 17.

    Radin EL (1976) Mechanical aspects of osteoarthritis. Bull Rheum Diseases 26:862–865

  18. 18.

    Reckling FW, Dillon WL (1977) The bone-cement interface temperature during total joint replacement. J Bone Jt Surg 59-A:80–86

  19. 19.

    Schatzker J, Horne JG, Sumner-Smith G, Sanderson R, Murnaghan JP (1975) Methylmethacrylate cement: its curing temperature and effect on articular cartilage. Can J Surg 18:172–178

  20. 20.

    Schatzker J, Ha'Eri GB, Chapman M (1978) Methylmethacrylate as an adjunct in the internal fixation of intertrochanteric fractures of the femur. J Trauma 18:732–735

  21. 21.

    Stevens J, Freeman PA, Nordon BEC, Barnett E (1962) The incidence of osteoporosis in patients with femoral neck fracture. J Bone Jt Surg 44-B:520–527

  22. 22.

    Sumner-Smith G, Waters EH (1976) The adjunctive use of methylmethacrylate bone cement in the stabilization of multiple fractures. J Am An Hosp Ass 12:778–781

  23. 23.

    Szyskowitz R, Cockin J (1974) Internal fixation of bone defects using bone cement and plates: an experimental study. J Bone Jt Surg 56-B:198–199

  24. 24.

    Willert JG, Ludwig J, Semlitsch M (1974) Reaction of bone to methylmethacrylate after hip arthroplasty. J Bone Jt Surg 56-A: 1368–1382

  25. 25.

    Yablon IG (1976) The effect of methylmethacrylate on fracture healing. Clin Orthop 114:358–363

  26. 26.

    Yablon IG, Paul GR (1976) The augmentive use of methylmethacrylate in the management of pathological fractures. Surg Gynecol Obstet 143:177–183

  27. 27.

    Zarek JM (1966) Dynamic considerations in load bearing bones with special reference to osteosynthesis and articular cartilage. In: Evans FG (ed) Studies of the anatomy and function of bone and joints. Springer, Berlin Heidelberg New York, pp 41–51

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Author information

Correspondence to Paul A. Manley DVM, MSc.

Additional information

Supported by University of Guelph Advisory Board Research Grant

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Manley, P.A., McKeown, D.B., Schatzker, J. et al. Replacement of epiphyseal bone with methylmethacrylate: Its effect on articular cartilage. Arch. Orth. Traum. Surg. 100, 3–10 (1982). https://doi.org/10.1007/BF00381536

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Keywords

  • Public Health
  • Femoral Neck
  • Articular Cartilage
  • Trabecular Bone
  • Degenerative Change