Current Genetics

, Volume 9, Issue 7, pp 529–532 | Cite as

UV-inducible proteins in Saccharomyces cerevisiae

  • Mark Rolfe
Article
Received:

Summary

Two UV-inducible proteins have been detected in the yeast, Saccharomyces cerevisiae. The proteins have molecular weights of 78,000 Daltons and 23,000 Daltons. This induction is specific for UV-irradiation as exposure to X-rays, mitomycin C and heat shock does not result in the synthesis of the proteins. The larger (78 kD) protein is induced in various rad strains and in a π° cir° strain. Attempts are being made to isolate the genes coding for these inducible proteins.

Keywords

Yeast UV-inducible proteins rad mutants 
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References

  1. Baker TI (1983) Mol Gen Genet 190:295–299Google Scholar
  2. Casadaban MJ, Cohen SN (1980) Proc Natl Acad Sci USA 76: 4530–4533Google Scholar
  3. Das SK, Loeb LA (1984) Mutant Res 131:97–99Google Scholar
  4. Fabre F, Roman F (1977) Proc Natl Acad Sci USA 74:1667–1671Google Scholar
  5. Fogliano M, Schendel PF (1981) Nature 289:196–198Google Scholar
  6. Game JC (1982) In: Spencer JFT, Spencer DM, Smith ARW (eds) Yeast genetics: Fundamental and applied aspects. Springer, New York, 1983Google Scholar
  7. Holliday R (1964) Genetics 50: 323–335Google Scholar
  8. Kenyon CJ, Walker GC (1980) Proc Natl Acad Sci USA 77:2819 to 2823Google Scholar
  9. Kmiec E, Holloman WK (1982) Cell 29:367–374CrossRefPubMedGoogle Scholar
  10. Kmiec E, Holloman WK (1983) Cell 33:857–864Google Scholar
  11. Kmiec E, Holloman WK (1984) Cell 36:593–598Google Scholar
  12. Kmiec E, Kroeger PE, Brougham MJ, Holloman WK (1983a) Cell 34:919–929Google Scholar
  13. Kmiec E, Brougham M, Yarnall M, Kroeger PE, Holloman WK (1983b) In: Gozzarelli N (ed) Mechanisms of DNA replication and recombination. UCLA Symp Mot Cell Biol New Ser 10:753–760Google Scholar
  14. Krueger JH, Walter GC (1984) Proc Natl. Acad Sci USA 81: 1499–1503Google Scholar
  15. Laemmli UK (1970) Nature 227:680–682PubMedGoogle Scholar
  16. Leaper S, Resnick MA, Holliday R (1980) Genet Res Camb 35: 291–307Google Scholar
  17. Lee MG (1983) PhD Thesis, CNAA LondonGoogle Scholar
  18. Lee MG, Yarranton GT (1982) Mol Gen Genet 185:245–250Google Scholar
  19. Moustachi E, Schwencke J (1982) Mol Gen Genet 185:290–295Google Scholar
  20. Prakash L (1977) Mutat Res 45: 13–20Google Scholar
  21. Resnick MA, Holliday R (1971) Mol Gen Genet 111:171–184Google Scholar
  22. Reynolds RJ, Friedberg EC (1981) J Bacteriol 146:692–704Google Scholar
  23. Ruby SW, Szostak JW, Murray AW (1983) Methods Enzymol 101:253–268Google Scholar
  24. Sherman F, Fink GR, Lawrence CW (1971) Methods in yeast genetics. Laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NYGoogle Scholar
  25. Siede W, Eckardt F, Brendel M (1983) Mol Gen Genet 190:406 to 412Google Scholar
  26. Stadler D, Moyer R (1981) Genetics 98:763–774Google Scholar
  27. Walker GC (1984) Microbiol Rev 48:60–93PubMedGoogle Scholar
  28. Wang SY, Varghese AJ (1967) Biochem Biophys Res Commun 29:543–549Google Scholar

Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • Mark Rolfe
    • 1
  1. 1.Genetics DivisionNational Institute for Medical ResearchLondonGreat Britain

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