Early reaction type allergies and diseases of the respiratory passages in employees from persulphate production

  • R. Wrbitzky
  • H. Drexler
  • S. Letzel
Original Article

DOI: 10.1007/BF00381054

Cite this article as:
Wrbitzky, R., Drexler, H. & Letzel, S. Int. Arch Occup Environ Heath (1995) 67: 413. doi:10.1007/BF00381054

Abstract

The prevalence of positive skin-prick test reactions to ammonium persulphate and potassium persulphate (1% and 5% solutions) was tested in a cross-sectional study on 52 employees of a company producing persulphates after a case of “persulphate asthma” was observed. A random test of 13 persons without occupational exposure to persulphates served as controls; among them all the skin-prick test reactions were negative. Eight company employees showed a positive skin-prick test reaction to at least one of the persulphate solutions tested. Employees showed lower lung function results with a positive prick test reaction than did employees with a negative result. The positive skin-prick reactions correspond well to the anamnestic data and indicate a possible relationship to obstructive ventilation disorders. The results therefore suggest an IgE-induced, allergic pathomechanism of “persulphate asthma” triggered by persulphates.

Key words

Persulphate Early reaction type allergy Skin-prick test Occupational disease Occupational asthma 

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • R. Wrbitzky
    • 1
  • H. Drexler
    • 1
  • S. Letzel
    • 1
  1. 1.Institute and Outpatient Clinic for Occupational Social and Environmental MedicineUniversity of Erlangen-NürnbergErlangenGermany

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