Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Milk and blood levels of silicon and selenium status in bovine mastitis

  • 58 Accesses

  • 11 Citations

Abstract

Milk and blood levels of silicon, selenium and the selenoenzyme glutathione peroxidase (GSH-Px) were measured in 20 healthy and 21 mastitic cows. In milk samples from healthy quarters the mean silicon concentration was 0.81 and in affected ones 0.39 ppm. In serum the mean silicon values were 1.63 and 1.02 ppm respectively. The selenium status was not altered but the level of erythrocyte GSH-Px was lowered in mastitic animals. Silicon is known to have marked effects on free radical formation, lipid peroxidation and macrophage activity. Its possible role in infection and inflammation is evaluated. Some of the functions of silicon may resemble those of selenium. The possibility of lowered levels of silicon and of the selenoenzyme in mastitis calls for experimentation with dietary or pharmaceutical supplementation of these trace elements.

This is a preview of subscription content, log in to check access.

References

  1. Akiya, S., Motohashi, N. & Niwase, T. 1960. Studies on the silica in animal tissue. Bulletin of the Tokyo Medical and Dental University, 7, 327–350

  2. Allison, A.C. 1976. Fluorescence microscopy of lymphocytes and mononuclear phagocytes and the use of silicate to eliminate the latter. In: B.R. Bloom & J.R. David (eds), In vitro methods in cell-mediated and tumor immunity. (Academic Press Inc., New York), 395–404

  3. Archibald, J. G. & Fenner, H. 1957. Silicon in cow milk. Journal of Dairy Science, 40, 703–706

  4. Atroshi, F., Kangasniemi, R., Honkanen-Buzalski, T. & Sandholm, M. 1982. Beta-lactoglobulin phenotypes in Finnish Ayrshire and Friesian cattle, with special reference to mastitis. Acta Veterinaria Scandinavica, 23, 135–143

  5. Atroshi, F., Sankari, S., Osterberg, S. & Sandholm, M. 1981. Variation of erythrocyte glutathione peroxidase activity in Finnsheep. Research in Veterinary Science, 31, 267–271

  6. Atroshi, F., Sankari, S. & Kaipainen, P. 1985. Erythrocyte and liver characteristics in low and high glutathione Finnsheep. Pharmacological Research Communications, 17, 23–32

  7. Atroshi, F., Parantainen, J., Sankari, S. & Osterman, T. 1986. Prostaglandins and glutathione peroxidase in bovine mastitis. Research in Veterinary Science, 40, 361–366

  8. Bailey, C.B. 1967. Siliceous urinary calculi in calves: prevention by addition of sodium chloride in the diet. Science, 155, 696–697

  9. Binnerts, W.T., Rijken, J. & Viets, T.C. 1984. The selenium content in milk as indicator of the selenium status in cows. In: Trace element—analytical chemistry in medicine and biology, Vol. 3, (Walter de Gruyter & Co., Berlin/New York), 129–137

  10. Boyne, R. & Arthur, J.R. 1979. Alterations of neutrophil function in Sedeficient cattle. Journal of Comparative Pathology, 89, 151–158

  11. Carlisle, E.M. 1974. Silicon as an essential element. Federation Proceedings, 33, 1758–1766

  12. Chaplin, C.H. 1969. Loss of both breasts from injections of silicone (with additive). Plastic and Reconstructive Surgery, 44, 447–450

  13. Coombs, J., Spanis, C. & Volcani, B.E. 1967. Studies on the biochemistry and fine structure of silica shell formation in diatoms. Photosynthesis and respiration in silicon starvation synchrony of Naviculapelliculosa. Plant Physiology, 42, 1607–1611

  14. Craggs, R.I., King, R.H.M. & Thomas, P.K. 1984. The effect of suppression of macrophage activity on the development of allergic neuritis. Acta Neuropathology, 62, 316–323

  15. Dobbie, J.W. & Smith, J.B. 1982. The silicon content of body fluids. Scottish Medical Journal, 27, 17–19

  16. Dormandy, T.L. 1983. An approach to free radicals. Lancet, 2, 1010–1014

  17. Flohe, L. & Zimmermann, R. 1970. Role of GSH peroxidase in protecting the membrane of rat liver mitochondria. Biochimica Biophysica Acta, 223, 210–213

  18. Flohe, L., Gunzler, W.A. & Schock, H.H. 1973. Glutathione peroxidase: a selenoenzyme. FEBS Letters, 32, 132–134

  19. Ghadirian, E. & Kongshavn, P.A.L. 1984. Effect of silica on resistance of mice to entamoeba histolytica infection. Infective Immunity, 45, 399–402

  20. Greene, R.L. & Street, B.G. 1984. Conducting organic materials. Science, 226, 651–656

  21. Gunther, M. 1965. Acute mastitis. Lancet, 1, 175–180

  22. Higson, F.K. & Jones, O.T.G. 1984. Oxygen radical production by horse and pig neutrophils induced by a range of chrystals. Journal of Rheumatology, 11, 735–741

  23. Klastrup, O. & Schmidt Madsen, P. 1974. Nordiske recommendationer vedrorende mastitisundersogelser af kirtelprover. Nordisk Veterinaermedicin, 26, 197–204

  24. Koike, S., Kuno, Y. & Morita, H. 1982. The effects of silica on lipid peroxidation, and the production of superoxide radicals by phagocytizing rabbit macrophages. Nippon Eisequku Zasshi, 37, 510–515

  25. Loeper, J., Goy-Loeper, J., Rozensztajn, L. & Fragny, M. 1979. The antiatheromatous action of silicon. Atherosclerosis, 33, 397–408

  26. Maas, J.P. 1983. Diagnosis and management of selenium responsive diseases in cattle. The Compendium of Continuing Education in Practitioning Veterinary, 5, S393-S399

  27. Mauras, Y., Riberi, P., Cartier, F. & Allain, P. 1980. Increase in blood silicon concentrations in patients with renal failure. Biomedicine, 33, 228–230

  28. McCay, P.B., Gibson, D.D., Fong, K.L. & Hornbrook, K.R. 1976. Effect of glutathione peroxidase activity on lipid peroxidation in biological membranes. Biochimica Biophysica Acta, 431, 459–468

  29. Oksanen, H.E., Sandholm, M. 1970. Selenium content of Finnish forage crops. Journal of the Scientific Agricultural Society of Finland, 42, 251–254

  30. Parantainen J. 1985. Trace elements as possible keys to biological semiconduction: pharmacological implications. 4th South-East Asian/ Western Pacific Meeting of Pharmacologists. Penang, Malaysia, Abstr. p6

  31. Parnham, M.J., Winkelmann, J. & Leyck, S. 1983. Macrophage, lymphocyte and chronic inflammatory responses in selenium deficient rodents. Association with decreased glutathione peroxidase activity. International Journal of Immunopharmacology, 5, 455–461

  32. Perry, R.R., Jaques, D.P., Lesar, M.S.L., d'Avis, J.C. & Peterson, H.D. 1985. Mycobacterium avium infection in a silicone-injected breast. Plastic and Reconstructive Surgery, 75, 104–106

  33. Sankari, S. & Atroshi, F. 1983. Effect of dietary selenium on erythrocyte glutathione peroxidase and blood selenium in two types of Finnsheep genetically selected for high and low glutathione peroxidase activity. Zentralblatt fur Veterinarmedizin A, 30, 452–458

  34. Schulze, W.D., Thompson, P.D. & Bright, S.A. 1978. Inflammatory response of the bovine mammary gland to an irritant in the streak canal. American Journal of Veterinary Research, 39, 785–790

  35. Schwarz, K. 1974. Recent dietary trace element research, exemplified by tin, fluorine, and silicon. Federation Proceedings, 33, 1748–1757

  36. Schwarz, K. 1978. Significance and functions of silicon in warm-blooded animals. Review and outlook. In: G. Bendz & I. Lindqvist (eds), Nobel symposium 40, 1977, (Plenum Press, New York), 207–230

  37. Smith, K.L., Harrison, J.H., Hancock, D.D., Todhunter, D.A. & Conrad, H.R. 1984. Effect of vitamin E and selenium supplementation on incidence of clinical mastitis and duration of clinical symptoms. Journal of Dairy Science, 67, 1293–1297

  38. Snedecor G.W. & Cochran W.G. 1967. Statistical methods. 6th edition, (Iowa State University Press of America)

  39. Symmers, W. St C. 1968. Silicone mastitis in ‘topless’ waitresses and some other varieties of foreign-body mastitis. British Medical Journal, 3, 19–22

  40. Tansey, F.A. & Brosnan, C.F. 1982. Protection against experimental allergic neuritis with silica quartz dust. Journal of Neuroimmunology, 3, 169–179

  41. Varo P. 1979. Kivennaisainetaulukko (Tables of trace elements, in Finnish), Otava.

  42. Voronkov, M.G., 1975. Silizium und Leben K. Rhlmann (ed), (Akademie-Verlag, 071 Berlin)

  43. Weiss, A. 1978. Isolation and characterization of a characteristic phosphatosilicate from human lungs with silicosis. In: G. Bends & I. Lindqvist (eds), Biochemistry of silicon and related problems. Nobel Symposium 40, 1977, (Plenum Press, New York)

  44. Zsoldos, T., Tigyi, A., Montsk, T. & Puppi, A. 1983. Lipid peroxidation in the membrane damaging effect of silica-containing dust on rat lungs. Experimental Pathology, 23, 73–77

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Parantainen, J., Tenhunen, E., Kangasniemi, R. et al. Milk and blood levels of silicon and selenium status in bovine mastitis. Vet Res Commun 11, 467–477 (1987). https://doi.org/10.1007/BF00380629

Download citation

Keywords

  • Silicon
  • Glutathione
  • Lipid Peroxidation
  • Selenium
  • Blood Level