Sodium citrate ingestion and its effects on maximal anaerobic exercise of different durations

  • Lars Mc Naughton
  • Rod Cedaro


The effects of an alkalising agent were studied in ten subjects who participated in anaerobic testing on a cycle ergometer to determine the effectiveness of sodium citrate (0.5 g·kg−1 body mass) as an ergogenic aid during exercise of 10-s, 30-s, 120-s and 240-s duration. Blood was collected prior to, after ingestion of sodium citrate (NaHCO3), and postexercise, from a heated (43–46°C) fingertip and analysed immediately postcollection for pH, partial pressure of oxygen and carbon dioxide, base excess and blood bicarbonate. Total work undertaken (kJ) and peak power (W) achieved during the tests was also obtained via a work monitor unit. The results indicated that a dose of 0.5 g sdkg−1 body mass sodium citrate had no ergogenic benefit for exercise of either 10-s or 30-s duration. Blood bicarbonate concentrations, however, were significantly increased (P<0.05) following ingestion of the citrate during these trials. Exercise periods of 120 s and 240 s were significantly increased (P<0.05) above the control and placebo conditions following sodium citrate ingestion. Blood bicarbonate concentrations were again increased above control and placebo conditions and blood lactate concentrations were also increased following the citrate trials. The pH decreased significantly (P<0.05) in all trials below the control and placebo conditions. On the basis of the exercise undertaken in this study we would suggest that a dose of 0.5 g·kg−1 body mass of sodium citrate could improve anaerobic exercise performance of 120-s and 240-s duration.

Key words

Alkalising agent Anaerobic pH Blood bicarbonate Sodium citrate 


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  1. Bouissou P, Defer G, Guezennec CY, Estrade PY, Serrurier B (1988) Metabolic and blood catecholamine responses to exercise during alkalosis. Med Sci Sports Exerc 20:228–232Google Scholar
  2. Bozzuto TM (1988) Severe metabolic acidosis secondary to exertional hyperlactemia. Am J Emerg Med 6:134–136Google Scholar
  3. Costill DL, Verstappen F, Kuipers H, Janssen E, Fink W (1984) Acid base balance during repeated bouts of exercise: influences of HCO3. Int J Sports Med 5:228–231Google Scholar
  4. Donaldson SKB, Hermansen L (1978) Differential direct effects of H+ and Ca2+-activated force of skinned fibres from the soleus, cardiac, adductor magnus muscle of rabbits. Pflügers Arch 376:55–65Google Scholar
  5. Fabiato A, Fabiato F (1978) Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiac and skeletal muscles. J Physiol 276:233–235Google Scholar
  6. Forster HV, Dempsey JA, Thompson J, Vidruk E, doPico GA (1972) Estimation of arterial PO2, PCO2, pH and lactate from arterialized venous blood. J Appl Physiol 32:134–137Google Scholar
  7. Goldfinch J, McNaughton LR, Davies P (1988) Bicarbonate ingestion and its effects upon 400-m racing time. Eur J Appl Physiol 57:45–48Google Scholar
  8. Hargreaves M (1990) Introduction. In: Fatigue in Sports and Exercise. Proceedings of the Symposium held in November in the Department of Physical Education and Recreation, Victorian University of Technology, Footscray, p (i)Google Scholar
  9. Hermansen L (1969) Anaerobic energy release. Med Sci Sports 1:32–38Google Scholar
  10. Hermansen L, Osnes J (1972) Blood and muscle pH after maximal exercise in man. J Appl Physiol 32:304–308Google Scholar
  11. Hirche H, Hombach V, Langhor HD, Wacker U (1972) Lactic acid permeation rate in working skeletal muscle during alkalosis and acidosis. Pflügers Arch 332:R73Google Scholar
  12. Horswill CA, Costill DL, Fink WJ, Flynn MG, Kirwan JP, Mitchell JB, Houmard JA (1988) Influence of sodium bicarbonate on sprint performance, relationship to dosage. Med Sci Sports Exerc 20:566–569Google Scholar
  13. Jacobs I, Tesch PA, Bar-Or O, Karlsson J, Dotan R (1983) Lactate in human skeletal muscle after 10 and 30 s of supramaximal exercise. J Appl Physiol Respir Environ Exerc Physiol 55:365–367Google Scholar
  14. Johnson WR, Black DH (1953) Comparison of effects of certain blood alkalinizer and glucose upon competitive endurance performance. J Appl Physiol 5:577–578Google Scholar
  15. Jones NL, Sutton JR, Taylor R, Toews CJ (1977) Effect of pH on cardiorespiratory and metabolic responses to exercise. J Appl Physiol 43:959–964Google Scholar
  16. Katz A, Costill DL, King DS, Hargreaves M, Fink WJ (1984) Maximal exercise tolerance after induced alkalosis. Int J Sports Med 5:107–110Google Scholar
  17. Keppel G (1982) Design and analysis: a researcher's handbook, 2nd edn. Prentice Hall, Englewood Cliffs, N.J.Google Scholar
  18. Lavender G, Bird SR (1989) Effects of sodium bicarbonate ingestion upon repeated sprints. Br J Sports Med 23:41–45Google Scholar
  19. Lehninger AL (1975) Biochemistry, 2nd edn. Worth, New YorkGoogle Scholar
  20. Mainwood GW, Cechetto D (1980) The effect of bicarbonate concentration on fatigue and recovery in isolated rat diaphragm. Can J Physiol Pharmacol 58:624–632Google Scholar
  21. Margaria R, Aghemo P, Sassi G (1971) Effects of alkalosis on performance and lactate formation in supramaximal exercise. Int Z Angew Physiol 29:215–223Google Scholar
  22. Maughan RJ, Leiper JB, Litchfield PE (1986) The effects of induced acidosis and alkalosis on isometric endurance capacity in man. In: Dotson CO, Humphrey JH (eds) Exercise physiology, current selected research, vol. 2. AMS Press, New York, pp 73–82Google Scholar
  23. McCartney N, Heigenhauser GFC, Jones NL (1983) Effects of pH on maximal power output and fatigue during short term dynamic exercise. J Appl Physiol Respir Environ Exerc Physiol 55:225–229Google Scholar
  24. McKenzie DC, Coutts KD, Stirling DR, Hoeben HH, Kuzara G (1986) Maximal work production following two levels of artificially induced metabolic alkalosis. J Sports Sci 4:35–38Google Scholar
  25. McLellan TM, Gass GC (1989) Metabolic and cardio-respiratory responses relative to the anaerobic threshold. Med Sci Sports Exerc 21:191–198Google Scholar
  26. Mc Naughton LR (1990) Sodium citrate and anaerobic performance: implications of dosage. Eur J Appl Physiol 61:392–397Google Scholar
  27. Mc Naughton LR (1991) Bicarbonate ingestion: implications of dosage on 60 s cycle ergometry. J Sports Sci (in press)Google Scholar
  28. Mc Naughton LR, Cedaro R (1991) Effects of sodium bicarbonate on rowing ergometer performance in elite rowers. Aust J Sci Med Sport (in press)Google Scholar
  29. Mc Naughton LR, Curtin R, Goodman G, Perry D, Turner B, Showell C (1991) Anaerobic work and power output during cycle ergometer exercise: effects of bicarbonate loading. J Sports Sci 9:151–160Google Scholar
  30. Medbo JI, Sejersted OM (1985) Acid-base and electrolyte balance after exhausting exercise in endurance-trained and sprint-trained subjects. Acta Physiol Scand 125:97–109Google Scholar
  31. Parry-Billings M, MacLaren DPM (1986) The effect of sodium bicarbonate and sodium citrate ingestion on anaerobic power during intermittent exercise. Eur J Appl Physiol 55:224–229Google Scholar
  32. Robin ED (1961) of men and mitochondria: intracellular and sub-cellular acid-base relations. New Engl J Med 265:780–785Google Scholar
  33. Sahlin K (1978) Intracellular pH and energy metabolism in skeletal muscle of man. Acta Physiol Scand 103 [Suppl 455]:1–56Google Scholar
  34. Sahlin K (1990a) Metabolic factors in fatigue. In: Fatigue in sports and exercise. Proceedings of Symposium held in November in the Department of Physical Education and Recreation, Victorian University of Technology, Footscray, pp 23–32Google Scholar
  35. Sahlin K (1990b) Regulation of lactate formation during exercise. In: Fatigue in sports and exercise. Proceedings of Symposium held in November in the Department of Physical Education and Recreation, Victorian University of Technology, Footscray, pp 75–85Google Scholar
  36. Simmons RWF, Hardt AB (1973) The effect of alkali ingestion on the performance of trained swimmers. J Sports Med 13:159–163Google Scholar
  37. Sutton J, Jones N, Toews CJ (1981) Effect of pH on muscle glycolysis during exercise. Clin Sci 61:331–338Google Scholar
  38. Wilkes D, Gledhill N, Smyth R (1983) Effect of acute induced metabolic alkalosis on 800-m racing time. Med Sci Sports Exerc 15:277–280Google Scholar

Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Lars Mc Naughton
    • 1
  • Rod Cedaro
    • 2
  1. 1.Centre for Physical EducationUniversity of Tasmania — LauncestonLauncestonAustralia
  2. 2.Tasmanian Institute of SportUniversity of TasmaniaMowbrayAustralia

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