Current Genetics

, Volume 7, Issue 4, pp 323–325

Some genetical and biochemical attempts to elucidate the energetics of sugar uptake and explain the Kluyver effect in the yeast Kluyveromyces lactis

  • K. -D. Entiani
  • J. A. Barnett
Original Articles

DOI: 10.1007/BF00376078

Cite this article as:
Entiani, K.D. & Barnett, J.A. Curr Genet (1983) 7: 323. doi:10.1007/BF00376078


A mutant of Kluyveromyces lactis is described which did not grow with substrates giving the Kluyver effect. In addition it could not grow with non-fermentable carbon sources, although it was not respiratory deficient. Abolition of respiration by cyanide also caused inability to grow with substrates showing the Kluyver effect in the wild-type strain. When the yeasts were using substrates showing the Kluyver effect, shifting to anaerobic conditions gave an immediate decrease in the intracellular concentration of d-glucose 6-phosphate. The results obtained were consistent with the need of a common respiratory and/or anabolic pathway for the utilization of these substrates.

Key words

Disaccharide utilization Kluyveromyces lactis Anaerobic Aerobic Kluyver effect Respiratory chain 

Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • K. -D. Entiani
    • 1
  • J. A. Barnett
    • 2
  1. 1.Physiologisch-chemisches InstitutUniversität TübingenTübingenGermany
  2. 2.School of Biological SciencesUniversity of East AngliaNorwichEngland

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