International Urogynecology Journal

, Volume 5, Issue 2, pp 102–105 | Cite as

Malignant lymphoma of the bladder and female urethra

  • R. H. W. Simpson
  • R. S. Amin
  • R. D. Pocock
Review Article


Primary malignant non-Hodgkin's lymphomas account for 0.4% of malignant neoplasms arising in the bladder and female urethra, but do not comprise a uniform group, and three subgroups can be identified which account for a majority of cases. The most common is a low-grade B-cell lymphoma similar to neoplasms arising in the mucosa-associated lymphoid tissue at other sites — so-called ‘MALTomas’. These generally display indolent behavior. A second group accounting for approximately one-fifth of cases is composed almost entirely of large lymphoid cells, and these tumors have a poor prognosis. A third possible group comprises only a few patients who present with diffuse thickening of the bladder wall, and have a poor prognosis. The authors present a new case which suggests that this latter group may be of T-cell origin. In addition to these three subtypes, others no doubt await recognition. The different forms of primary lymphoma appear to require different treatments, and some guidelines are proposed.


Bladder neoplasms Lymphoma Urethral neoplasms 


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Copyright information

© The International Urogynecology Journal 1994

Authors and Affiliations

  • R. H. W. Simpson
    • 1
  • R. S. Amin
    • 2
  • R. D. Pocock
    • 3
  1. 1.Department of Histopathology, Postgraduate Medical SchoolUniversity of ExeterUK
  2. 2.Department of OncologyRoyal Devon and Exeter HospitalExeterUK
  3. 3.Department of UrologyRoyal Devon and Exeter HospitalExeterUK

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