International Urogynecology Journal

, Volume 4, Issue 5, pp 259–261 | Cite as

Does progesterone cause an irritable bladder?

  • A. Cutner
  • G. Burton
  • L. D. Cardozo
  • B. G. Wise
  • D. Abbott
  • J. Studd
Original Article


Nine women with primary ovarian failure, who were having their artificial menstrual cycles manipulated with physiological levels of estrogen and high doses of progesterone, were entered into the study. They filled in urinary symptom questionnaires and had urodynamic investigations in the two phases of treatment: estrogen and progesterone, and estrogen alone. The number of voids per 24 hours was significantly greater in the progesterone phase, as was the end filling pressure on cystometry. This is the first report in the literature of the effects of high-dose progesterone on the lower urinary tract.


Lower urinary tract Progesterone 


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Copyright information

© The International Urogynecology Journal 1993

Authors and Affiliations

  • A. Cutner
    • 1
  • G. Burton
    • 2
  • L. D. Cardozo
    • 1
  • B. G. Wise
    • 1
  • D. Abbott
    • 1
  • J. Studd
    • 1
  1. 1.King's College Hospital Registrar Rotation, Urodynamic Unit, King's College HospitalDenmark Hill, LondonUK
  2. 2.Lister HospitalLondonUK

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