Abstract
The influence of antifoam agents on the liquid-phase mass transfer coefficient in stirred tank and bubble column bioreactors is studied. A physical model based on a surface-renewal concept and additional data in 40-dm3 bubble column bioreactor are presented. Comparisons between the physical model and the data indicate that the model predicts the maximum influence of antifoam agents on the liquid-phase mass transfer coefficient.
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Abbreviations
- a 1/m:
-
specific surface area
- D m2/s:
-
diffusivity
- D c m:
-
bubble column diameter
- d vs m:
-
bubble diameter
- g m/s2 :
-
gravitational acceleration
- k L m/s:
-
liquid-phase mass transfer coefficient
- k LO m/s:
-
liquid-phase mass transfer coefficient for clean surface
- N 1/s:
-
impeller speed
- Sc :
-
Schmidt number (v/D)
- U sg m/s:
-
superficial gas velocity
- ɛ W/kg:
-
energy dissipation rate per unit mass
- ɛ g :
-
gas hold-up
- μ Pa s:
-
viscosity
- v m2/s:
-
kinematic viscosity
- ρ kg/m3 :
-
density
- σ N/m:
-
surface tension
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Kawase, Y., Moo-Young, M. The effect of antifoam agents on mass transfer in bioreactors. Bioprocess Engineering 5, 169–173 (1990). https://doi.org/10.1007/BF00369581
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DOI: https://doi.org/10.1007/BF00369581