Über den Einfluß der Kationenkonzentration im Erythrocyten auf die Lage der Sauerstoff-Dissoziationskurve des Blutes

  • H. Sommerkamp
  • K. Riegel
  • P. Hilpert
  • K. Brecht


The interrelationship between oxygen affinity and cation concentration within the erythrocyte has been investigated, using blood samples from healthy adults, anemic children and erythrocyte suspensions whose cation concentration had been altered. It is shown that the position of the oxygen dissociation curve depends in part upon the cation concentration of the red blood cells; with a high intracellular cation concentration the dissociation curve shifts to the right, the opposite shift is seen with low cation concentration. The substitution of intracellular potassium by sodium does not influence the oxygen affinity unless the total cation concentration is changed.


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Copyright information

© Springer-Verlag 1961

Authors and Affiliations

  • H. Sommerkamp
    • 1
  • K. Riegel
    • 1
  • P. Hilpert
    • 1
  • K. Brecht
    • 1
  1. 1.Aus dem Physiologischen Institut und der Kinderklinik der Universität TübingenGermany

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