Mammalian Genome

, Volume 5, Issue 1, pp 15–18 | Cite as

The γ phosphorylase kinase gene, Phkg, maps to mouse Chromosome 5 near Gus

  • A. J. Maichele
  • J. S. Chamberlain
Original Contributions
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Abstract

Phosphorylase kinase is a multimeric regulatory enzyme in the glycogenolytic pathway. Interest in various types of phosphorylase kinase enzyme deficiency has focused attention on cloning and mapping the enzyme subunits. We report the mapping of the catalytic γ subunit gene, Phkg, to mouse Chromosome (Chr) 5 near β-glucuronidase (Gus), between alpha fetoprotein (Afp) and erythropoietin (Epo). In addition, PCR-based polymorphism assays have been developed for the human (EPO) and mouse erythropoietin genes, and a unique recombinant inbred strain distribution pattern has been defined for Epo, a distal anchor marker on mouse Chr 5.

Keywords

Erythropoietin Strain Distribution Phosphorylase Inbred Strain Subunit Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag New York Inc. 1994

Authors and Affiliations

  • A. J. Maichele
    • 1
  • J. S. Chamberlain
    • 1
  1. 1.Department of Human GeneticsUniversity of Michigan Medical SchoolAnn ArborUSA

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