Molecular Biology Reports

, Volume 12, Issue 3, pp 180–181 | Cite as

The intranuclear states of snRNP complexes

  • T. E. Martin
  • S. A. Monsma
  • J. M-J. Romac
  • G. P. Leser
Session 3: Structure of RNPs

Summary: Possible snRNP states

The data available at present suggest at least the following distinct states: a. free snRNP--possibly representing the active pool of recycling snRNP; b. loose snRNP:hnRNP complexes--these may represent snRNP involved in a “surveying” state prior to specific sequence interaction with pre-mRNA sites and perhaps characteristic of all polymerase II transcription sites; c. tight snRNP:hnRNP complexes--representing preformed spliceosome structures at specific sequence sites on pre-mRNA; d. ICG associated snRNP--function unknown, though possibly a storage structure of transiently inactive complexes.

Keywords

Function Unknown Specific Sequence Distinct State Sequence Site Storage Structure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Fakan S, Puvion E, and Spohr G (1976) Localization and characterization of newly synthesized nuclear RNA in isolated rat hepatocytes. Exp. Cell Res. 99, 155–164.Google Scholar
  2. Fakan S, Leser G, and Martin TE (1984) Ultra-structural distribution of nuclear ribonucleoproteins as visualized by immunocytochemistry on thin sections. J Cell Biol 98, 358–363.Google Scholar
  3. Fakan S, Leser G, and Martin TE (1986) Immuno-electron microscope visualization of nuclear ribonucleoprotein antigens with spread transcription complexes. J Cell Biol 103, 1153–1157Google Scholar
  4. Martin TE, Barghusen SC, Leser GP and Spear PG (1987) Redistribution of nuclear ribonucleoprotein antigens during herpes simplex virus infection. J Cell Biol. in press.Google Scholar
  5. Osheim YN, Miller OL Jr, and Beyer AL (1985) RNP particles at splice junction sequences on Drosophila chorion transcripts. Cell 43, 143–151.Google Scholar

Copyright information

© Martinus Nijhoff Publishers 1987

Authors and Affiliations

  • T. E. Martin
    • 1
  • S. A. Monsma
    • 1
  • J. M-J. Romac
    • 1
  • G. P. Leser
    • 1
  1. 1.Molecular Genetics & Cell BiologyUniversity of ChicagoUSA

Personalised recommendations