Chromosoma

, Volume 102, Issue 2, pp 71–80

Sex chromosomes, recombination, and chromatin conformation

  • Bruce D. McKee
  • Mary Ann Handel
Chromosoma Focus

Abstract

We review what is known about the transcriptional inactivation and condensation of heteromorphic sex chromosomes in contrast to the activation of homomorphic sex chromosomes during meiotic prephase in animals. We relate these cytological and transcriptional features to the recombination status of the sex chromosomes. We propose that sex chromosome condensation is a meiotic adaptation to prevent the initiation of potentially damaging recombination events in nonhomologous regions of the X and Y chromosome.

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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Bruce D. McKee
    • 1
  • Mary Ann Handel
    • 1
  1. 1.Department of ZoologyUniversity of TennesseeKnoxvilleUSA

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