Two members of the JAK family of protein tyrosine kinases map to Chromosomes 1p31.3 and 9p24
- 37 Downloads
A member of a new class of protein tyrosine kinases, JAK1, has been mapped to 1p31.3 by in situ hybridization and Southern blot analysis of a panel of mouse-human hybrid cell lines. A murine protein tyrosine kinase, related to, but distinct, from JAK1, was mapped by in situ hybridization to human Chromosome (Chr) 9p24 and 1p31.3.
Unable to display preview. Download preview PDF.
- Callen, D.F.: A mouse-human hybrid cell panel for mapping human chromosome 16. Ann Genet 29: 235–239, 1986.Google Scholar
- Callen, D.F., Baker, E., Eyre, H.J., and Lane, S.A.: An expanded mouse-human hybrid cell panel for mapping human chromosome 16. Ann Genet 33: 190–195, 1990.Google Scholar
- Firmbach-Kraft, I., Byers, M., Shows, T., Dalla-Favera, R., and Krolewski, J.J., tyk2 prototype of a novel class of non-receptor tyrosine kinase genes. Oncogene 5: 1329–1336, 1990.Google Scholar
- Hanks, S.K., Quinn, A.M., and Hunter, T.: The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains. Science 241: 42–52, 1988.Google Scholar
- Heisterkamp, N., Stephenson, J.R., Groffen, J., Hansen, P.F., de Klein, A., Bartram, C.F., and Grosveld, G.: Localisation of the c-ab1 oncogene adjacent to a translocation breakpoint in chronic myelocytic leukaemia. Nature 306: 239–242, 1983.Google Scholar
- Martinez, R., Mathey-Prevot, B., Bernards, A., and Baltimore, D.: Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart. Science 237: 411–414, 1987.Google Scholar
- Roberts, W.M., Look, A.T., Roussel, M.F., and Sherr, C.J.: Tandem linkage of human CSF-1 receptor (c-fms) and PDGF receptor genes. Cell 55: 655–661, 1988.Google Scholar
- Rothwell, V.M. and Rohrschneider, L.R.: Murine c-fms cDNA: Cloning sequence analysis and retroviral expression. Oncogene Res 1: 311–324, 1987.Google Scholar
- Sutherland, G.R., Baker, E., Callen, D.F., Hyland, V.J., May, B.K., Bawden, M.J., Healy, H.M., and Borthwick, I.A.: 5-Aminolevulinate synthase is at 3p21 and thus not the primary defect in X-linked sideroblastic anaemia. Am J Hum Genet 43: 331–335, 1988.Google Scholar
- Ullrich, A., Coussens, L., Hayflick, J.S., Dull, T.J., Gray, A., Tam, A.W., Lee, J., Yarden, Y., Libermann, T.A., Schlessinger, J., Downward, J., Mayes, E.L.V., Whittle, N., Waterfield, M.D., and Seeburg, P.H.: Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 309: 418–425, 1984.Google Scholar
- Wilks, A.F.: Isolation of two putative protein tyrosine kinases by application of the polymerase chain reaction. Proc Natl Acad Sci USA 86: 1603–1607, 1989.Google Scholar
- Wilks, A.F., Harpur, A.G., Kurban, R.R., Ralph, S.J., Zurcher, G., and Ziemiecki, A.: Two novel protein tyrosine kinases each with a second phosphotransferase-related catalytic domain define a new class of protein kinase. Mol Cell Biol 11: 2057–2065, 1991.Google Scholar