Current Genetics

, Volume 24, Issue 3, pp 268–270

Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae

  • Yury O. Chernoff
  • Irina L. Derkach
  • Sergey G. Inge-Vechtomov
Short Communications

DOI: 10.1007/BF00351802

Cite this article as:
Chernoff, Y.O., Derkach, I.L. & Inge-Vechtomov, S.G. Curr Genet (1993) 24: 268. doi:10.1007/BF00351802

Abstract

Previously, we have shown that plasmid-mediated multiplication of Saccharomyces cerevisiae wild-type SUP35 gene leads to omnipotent suppression and is incompatible with psi-factor, which is an endogenous extrachromosomal suppressor. Here, we describe a frequent de-novo appearance of psi-like factors in mitotic progeny of yeast transformants containing multicopy SUP35 gene.

Key words

Mistranslation Omnipotent suppression Plasmid Extrachromosomal element 

Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Yury O. Chernoff
    • 1
  • Irina L. Derkach
    • 1
  • Sergey G. Inge-Vechtomov
    • 1
  1. 1.Department of GeneticsSaint-Petersburg UniversitySaint-PetersburgRussia
  2. 2.Laboratory for Molecular Biology (M/C 067), Department of Biological SciencesUniversity of Illinois at ChicagoChicagoUSA

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