Mammalian Genome

, Volume 1, Issue 3, pp 165–170 | Cite as

B2-like repetitive sequence from the X Chromosome of the American mink (Mustela vison)

  • Marina V. Lavrentieva
  • Mark I. Rivkin
  • Alexander G. Shilov
  • Marina L. Kobetz
  • Igor B. Rogozin
  • Oleg L. Serov
Original Contributions


In analysis of the repeats from the mink X Chromosome (Chr), we have identified a B2-like repetitive sequence of 195 base pairs (bp) flanked by short direct repeats of 14 bp. It contains regions homologous to the split intragenic RNA polymerase III promoter and a 3′ A-rich region followed by an oligo(dA) sequence. A feature of the repeat is the presence of a perfect polypyrimidine tract 22 bp in length absent from the known Alu- and Alu-like sequences. Alignment of the mink B2-like sequence and mouse B2-consensus sequence allowed us to estimate their similarity as 55%. The repeat is present in 1–2×105 copies per mink genome and 2–4×103 copies per X Chr. In situ hybridization analysis demonstrated a similar distribution pattern of the B2-like repeat along the length of all the mink chromosomes including the X. We also observed the presence of mink B2-like hybridizable sequence in the genomes of other Carnivora species.


Distribution Pattern Base Pair Similar Distribution Hybridization Analysis Direct Repeat 
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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • Marina V. Lavrentieva
    • 1
  • Mark I. Rivkin
    • 1
  • Alexander G. Shilov
    • 1
  • Marina L. Kobetz
    • 1
  • Igor B. Rogozin
    • 1
  • Oleg L. Serov
    • 1
  1. 1.Siberian DepartmentInstitute of Cytology and Genetics, Academy of Sciences of the USSRNovosibirsk-90USSR

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