, Volume 9, Issue 2, pp 73–78 | Cite as

Adhesive arachnoiditis following myelography with various watersoluble contrast media

  • J. Suolanen


The history of the use of positive contrast media for myelography is discussed briefly with special reference to their toxic arachnoidal effects. Special cases of arachnoiditis due to watersoluble contrast media still in common use are presented. A case with severe neurological symptoms, rarely described in the earlier literature, is presented with cases of mild and severe arachnoidal adhesions observed on repeat myelography. In addition, one patient, who had been examined twice with 5 ml of meglumine iothalamate, showed no adhesions or deformities on repeat myelography or at autopsy. The influence os hyperosmolarity as a common irritating factor leading to arachnoiditis is discussed. Further results of myelography with the new contrast medium Metrizamide are awaited with interest as it is used in physiological osmotic concentrations.


Contrast Medium Special Reference Neurological Symptom Early Literature Meglumine 
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Arachnoidite adhesive après divers produits de contraste hydrosolubles


L'histoire des produits de contraste positif et leur effect toxique est brièvement discuté. On présente les cas d'arachnoidite causeés par les produits de contraste hydrosoluble dont on se sert ordinairement. Il y en a un cas de symptomes neurologiques assez graves qu'on ne trouve que rarement dans la littérature. Avec la myélographie répetée on trouve des adhésions arachnoidiennes légères et graves, ainsi qu'un cas de ré-myélographie normale (sans adhésions) et des examinations autoptiques sans signe d'arachnoidite chez un homme après deux examinations avec 5 ml Méglumine-Iothalamate. L'influence de l'hyperosmolarité sur les réactions adhésives et comme irritation ordinaire est discuté spécialement. Le futur du dernier produit de contrast Metrizamide sera intéressant puisque son usage en osmolarité physiologique.

Adhaesive Arachnoiditis nach verschiedenen wasserlöslichen Myelographie-Kontrastmitteln


Die Geschichte der positiven Kontrastmittelmyelographie und deren toxischer Effect auf die Arachnoidea wird kurz dargelegt. Es werden jene Fälle von Arachnoiditis vorgestellt, die auf die jetzt üblichen wasserlöslichen Kontrastmittel zurückzuführen sind, darunter auch ein Fall mit schweren neurologischen Symptomen, die kaum früher in der Literatur beschrieben worden sind. Bei wiederholter Myelographie werden sowohl leichte, wie auch schwere arachnoidale Adhaesionen beobachtet, bei einem Mann aber auch eine blande Re-Myelographie (ohne Adhaesionen) und keine autoptischen Zeichen einer Arachnoiditis nach zweimaligen Untersuchung mit je 5 ml Meglumin Iothalamat. Der Einfluß der Hyperosmolarität als Ursache der adhaesiven Veränderungen und als allgemeine Reizursache wird speziell besprochen. Von besonderem Interesse wird die Zukunft des neuesten Myelographie-Kontrastmittels Metrizamide sein, da es in physiologischer Osmolarität angewandt wird.


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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • J. Suolanen
    • 1
  1. 1.Department of RadiologyMalmis District HospitalPietarsaariFinland

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