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Current Genetics

, Volume 21, Issue 3, pp 261–263 | Cite as

Inactivation of the RAD1 excision-repair gene does not affect correction of mismatches on heteroduplex plasmid DNA in yeast

  • Xiaolin Kang
  • Bernard A. Kunz
Short Communication

Summary

The efficiency and direction of mismatch correction in the Saccharomyces cerevisiae SUP4-o gene were not altered by an excision-repair defect (rad1). Although excision-repair functions remove methylated adenine from yeast, adenine methylation at a GATC sequence in SUP4-o did not direct the correction of mismatches via excision repair.

Key words

Mismatch correction Saccharomyces cerevisiae Excision repair DNA methylation 

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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Xiaolin Kang
    • 1
  • Bernard A. Kunz
    • 1
  1. 1.Microbiology DepartmentThe University of ManitobaWinnipegCanada

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