Fine structure of cilia in rat cerebral cortex

  • Hans A. Dahl


Cilia have been demonstrated on granular neurons and astroglial cells in the fascia dentata, a part of the hippocampal region, in the rat. Every granular cell seems to possess one cilium, which shows an 8+1 pattern in the greater part of its length. This 8+1 pattern is shown to result from the displacement of one peripheral doublet of a 9+0 cilium into the middle of the cilium. The neuronal cilia have a two-centriole basal organization, and fine rootlets radiate from the basal body proper into the cytoplasm. The possible function and significance of these cilia are discussed on the basis of earlier literature.


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  1. Afanasiev, Y.-I., and E.-F. Kotovsky: To the question of the cerebral neuron division in the mammals. Path. Biol. 9, 880–883 (1961).Google Scholar
  2. Afzelius, B.: Electron microscopy of the sperm tail; results obtained with a new fixative. J. biophys. biochem. Cytol. 5, 269–278 (1959).Google Scholar
  3. : Some problems of ciliary structure and ciliary function, pp. 557–567 in: Biological structure and function (Proceedings of the First IUB/IUBS Internat. Symposium, Stockholm, 1961), vol. II (T. W. Goodwin and O. Lindberg eds.). London and New York: Academic Press 1961a.Google Scholar
  4. : The fine structure of the cilia from ctenophore swimming-plates. J. biophys. biochem. Cytol. 9, 383–394 (1961b).Google Scholar
  5. : The contractile apparatus in some invertebrate muscles and spermatozoa. M-1 in Proceedings of the Fifth Internat. Congr. for Electron Microscopy, Philadelphia 1962 (S. S. Breese jr. ed.), vol.2. New York and London: Academic Press 1962a.Google Scholar
  6. Personal communication 1962b.Google Scholar
  7. André, J.: Sur quelques détails nouvellement connus de l'ultrastructure des organites vibratiles. J. Ultrastruct. Res. 5, 86–108 (1961).Google Scholar
  8. Bargmann, W., u. A. Knoop: Elektronenmikroskopische Untersuchung der Krönchenzellen des Saccus vasculosus. Z. Zellforsch. 43, 184–194 (1955).Google Scholar
  9. Barnes, Barbara G.: Ciliated secretory cells in the pars distalis of the mouse hypophysis. J. Ultrastruct. Res. 5, 453–467 (1961).Google Scholar
  10. Blackstad, T. W.: Commisural connections of the hippocampal region in the rat, with special reference to their mode of termination. J. comp. Neurol. 105, 417–538 (1956).Google Scholar
  11. : A note on the electron microscopy of the fascia dentata. Acta morph. neerl.-scand. 3, 395–404 (1960).Google Scholar
  12. , and H. A. Dahl: Quantitative evaluation of structures in contact with neuronal somata. An electron microscopic study on the fascia dentata of the rat. Acta morph. neerl.-scand. 4, 329–343 (1962).Google Scholar
  13. , and Å. Kjærheim: Special axo-dendritic synapses in the hippocampal cortex: Electron and light microscopic studies on the layer of mossy fibers. J. comp. Neurol. 117, 133–159 (1961).Google Scholar
  14. Blinzinger, K.: Elektronenmikroskopische Untersuchungen am Ependym der Hirnventrikel des Goldhamsters (Mesocricetus auratus). Acta neuropath. (Berl.) 1, 527–532 (1962).Google Scholar
  15. Dahl, H. A.: Cilia in rat cerebral cortex. In: Proceedings of the annual meeting of the Scandinavian Electron Microscope Society, Uppsala, June 1962. J. Ultrastruct. Res. 8, 189–196 (1963).Google Scholar
  16. De Robertis, E.: Electron microscope observations on the submicroscopic organization of the retinal rods. J. biophys. biochem. Cytol. 2, 319–330 (1956a).Google Scholar
  17. : Morphogenesis of the retinal rods. An electron microscope study. J. biophys. biochem. Cytol. 2, Suppl., 209–218 (1956b).Google Scholar
  18. Fawcett, D. W.: Cilia and flagella., Chapt. 4, pp. 217–297, in: The Cell, vol. II. (J. Brachet and A. E. Mirsky eds.) New York and London: Academic Press 1961. 916 pp.Google Scholar
  19. Gibbons, I. R.: The relationship between the fine structure and direction of beat in gill cilia of a lamellibranch mollusc. J. biophys. biochem. Cytol. 11, 179–205 (1961).Google Scholar
  20. , and A. V. Grimstone: On flagellar structure in certain flagellates. J. biophys. biochem. Cytol. 7, 697–715 (1960).Google Scholar
  21. Gray, E. G.: The fine structure of the insect ear. Phil. Trans. B 243, 75–94 (1960).Google Scholar
  22. Hatai, S.: On the presence of the centrosome in certain nerve cells of the white rat. J. comp. Neurol. 11, 25–39 (1901a).Google Scholar
  23. : On the mitosis in the nerve cells of the cerebellar cortex of foetal cats. J. comp. Neurol. 11, 277–296 (1901b).Google Scholar
  24. Henneguy, L. F.: Sur les rapports des ciles vibratiles avec les centrosomes. Arch. Anat. micr. 1, 481 (1897).Google Scholar
  25. Holt, S. J., and R. M. Hicks: Studies on formalin fixation for electron microscopy and cytochemical staining purposes. J. biophys. biochem. Cytol. 11, 31–45 (1961).Google Scholar
  26. Kurosumi, K., T. Matsuzawa and S. Shibasaki: Electron microscope studies on the fine structures of the pars nervosa and pars intermedia, and their morphological interrelation in the normal rat hypophysis. Gen. comp. Endocr. 1, 433–452 (1961).Google Scholar
  27. Latta, H., A. B. Maunsbach and S. C. Madden: Cilia in different segments of the rat nephron. J. biophys. biochem. Cytol. 11, 248–252 (1961).Google Scholar
  28. Leeson, T. S.: Electron microscopy of the rete testis of the rat. Anat. Rec. 144, 57–68 (1962).Google Scholar
  29. Lenhossék, M. v.: Centrosom und Sphäre in den Spinalganglienzellen des Frosches. Arch. mikr. Anat. 46, 345–369 (1895).Google Scholar
  30. : Über Flimmerzellen. Verh. anat. Ges. (Jena) 12, 106–128 (1898).Google Scholar
  31. Maxwell, D. S., and D. C. Pease: The electron microscopy of the choroid plexus. J. biophys. biochem. Cytol. 2, 467–474 (1956).Google Scholar
  32. Mazia, D.: Mitosis and the physiology of cell division. Chap. 2, pp. 77–412, in: The Cell, vol. III. (J. Brachet and A. E. Mirsky eds.. New York and London: Academic Press 1961. 440 pp.Google Scholar
  33. Millen, J. W., and G. E. Rogers: An electron microscopic study of the chorioid plexus in the rabbit. J. biophys. biochem. Cytol. 2, 407–416 (1956).Google Scholar
  34. Munger, B. L.: A light and electron microscopic study of cellular differentiation in the pancreatic islets of the mouse. Amer. J. Anat. 103, 275–311 (1958).Google Scholar
  35. Murakami, M.: Elektronenmikroskopische Untersuchung der Neurosekretorischen Zellen im Hypothalamus der Maus. Z. Zellforsch. 56, 277–299 (1962).Google Scholar
  36. Nagano, T.: An electron microscopic observation on the cross-striated fibrils occurring in the human spermatocyte. Z. Zellforsch. 58, 214–218 (1962).Google Scholar
  37. Nauta, W. J. H.: Über die sogenannte terminale Degeneration im Zentralnervensystem und ihre Darstellung durch Silberimprägnation. Schweiz. Arch. Neurol. Psychiat. 66, 353–376 (1950).Google Scholar
  38. Palay, S. L.: An electron microscopical study of neuroglia, pp. 24–49, in: Biology of Neuroglia. (W. F. Windle ed.). Springfield (Ill.): Ch. C. Thomas 1958. 340 pp.Google Scholar
  39. : The fine structure of secretory neurons in the preoptic nucleus of the goldfish (Carassius auratus). Anat. Rec. 138, 417–444 (1960).Google Scholar
  40. : Structural peculiarities of the neurosecretory cells in the preoptic nucleus of the goldfish, Carassius auratus. Anat. Rec. 139, 262 (1961).Google Scholar
  41. Pappas, G. D.: Personal communication 1963.Google Scholar
  42. Pitelka, Dorothy R.: Observations on normal and abnormal cilia in Paramecium. M-7 in Proceedings of the Fifth Internat. Congr. for Electron Microscopy, Philadelphia 1962. (S. S. Breese jr. ed.), vol. 2. New York and London: Academic Press 1962.Google Scholar
  43. Porter, K. R.: The submicroscopic morphology of protoplasm. Harvey Lect., Ser. 51, 175–228 (1957).Google Scholar
  44. Rasmussen, A. J.: Ciliated epithelium and mucus-secreting cells in the human hypophysis. Anat. Rec. 41, 273–284 (1929).Google Scholar
  45. Rio-Hortega, P. del: Estudios sobre el centrosoma de las células nerviosas y neuróglicas delos vertebrados, en sus formas normal y anormales. Trab. Lab. invest. Biolog. Univ. Madrid 14, 117–153 (1916).Google Scholar
  46. Roth, L. E.: Observations on division stages in the protozoan hypotrich Stylonychia, pp. 241–244 in: Proceedings of the Fourth Internat. Conf. on Electron Microscopy, Berlin 1958. (W. Bargmann, D. Peters and C. Wolpers eds.), vol. II. Berlin-Göttingen-Heidelberg: Springer 1960.Google Scholar
  47. Rouiller, Ch., et E. Fauré-Fremiet: Ultrastructure des cinétosomes à l'état de repos et à l'état cilifère chez un cilié péritriche. J. Ultrastruct. Res. 1, 289–294 (1958).Google Scholar
  48. Satir, P.: On the evolutionary stability of the 9+2 pattern. J. Cell Biol. 12, 181–184 (1962).Google Scholar
  49. Shapiro, J. E., B. R. Hershenov and G. S. Tulloch: The fine structure of Haematoloechus spermatozoan tail. J. biophys. biochem. Cytol. 9, 211–217 (1961).Google Scholar
  50. Sjöstrand, F. S.: The ultrastructure of the inner segments of the retinal rods of the guinea pig eye as revealed by electron microscopy. J. cell. comp. Physiol. 42, 45–70 (1953).Google Scholar
  51. Slifer, Eleanor H., and S. S. Sekhon: The fine structure of the plate organs of the antenna of the honey bee, Apis mellifera linnaeus. Exp. Cell Res. 19, 410–414 (1960).Google Scholar
  52. : Fine structure of the sense organs on the antennal flagellum of the honey bee, Apis mellifera linnaeus. J. Morph. 109, 351–381 (1961).Google Scholar
  53. Sorokin, S.: Centrioles and the formation of rudimentary cilia by fibroblasts and smooth muscle cells. J. Cell Biol. 15, 363–377 (1962).Google Scholar
  54. Sotelo, J. R., and O. Trujillo-Cenóz: Electron microscope study on the development of ciliary components of the neural epithelium of the chick embryo. Z. Zellforsch. 49, 1–12 (1958).Google Scholar
  55. Tennyson, Virginia M., and G. D. Pappas: Electronmicroscope studies of the developing telencephalic choroid plexus in normal and hydrocephalic rabbits, pp. 267–318 in: Disorders of the Developing Nervous System (W. S. Fields and M. M. Desmond eds.). Springfield (Ill.): Ch. C. Thomas 1961. 567 pp.Google Scholar
  56. : An electron microscope study of ependymal cells of the fetal, early postnatal and adult rabbit. Z. Zellforsch. 56, 595–618 (1962).Google Scholar
  57. Tokuyasu, K., and E. Yamada: The fine structure of the retina studied with the electron microscope. IV. Morphogenesis of outer segments of retinal rods. J. biophys. biochem. Cytol. 6, 225–230 (1959).Google Scholar
  58. Vegge, T.: Ultrastructure of normal human trabecular endothelium. Acta ophthal. (Kbh.) 41, 193–199 (1963).Google Scholar
  59. Walberg, F.: An electron microscopic study of the inferior olive in the cat. J. comp. Neurol. 120, 1–17 (1963).Google Scholar
  60. Whitear, M.: Chordotonal organs in crustacea. Nature (Lond.) 187, 552 (1960).Google Scholar
  61. Wilson, E. B.: The cell in development and heredity. Third ed. New York: MacMillan Company 1925. 1232 pp.Google Scholar

Copyright information

© Springer-Verlag 1963

Authors and Affiliations

  • Hans A. Dahl
    • 1
  1. 1.Anatomical InstituteUniversity of OsloNorway

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