Molecular and General Genetics MGG

, Volume 126, Issue 1, pp 53–69 | Cite as

Isolation and characterization of a ribonuclease III deficient mutant of Escherichia coli

  • Peter Kindler
  • Till Uwe Keil
  • Peter Hans Hofschneider


A mutant of E. coli K 12 AB301 RNAase 19 - , selected for its inability to degrade double-stranded RNA, has been isolated and shown to have less than 1% of RNAase III-activity related to the parental strain.


Parental Strain Deficient Mutant 
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trichloracetic acid


replicative form of phage-RNA









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Copyright information

© Springer-Verlag 1973

Authors and Affiliations

  • Peter Kindler
    • 1
  • Till Uwe Keil
    • 1
  • Peter Hans Hofschneider
    • 1
  1. 1.Max-Planck-Institut für BiochemieMartinsried bei MünchenGermany

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