Molecular and General Genetics MGG

, Volume 218, Issue 3, pp 559–564 | Cite as

Homeosis and the interaction of zeste and white in Drosophila

  • C.-ting Wu
  • Richard S. Jones
  • Paul F. Lasko
  • William M. Gelbart
Short Communications


Transvection effects in Drosophila melanogaster suggest a form of gene modulation that is responsive to the proximity of homologous genes. These effects have been well characterized at bithorax and decapentaplegic, and in the interaction between the zeste and white genes. The mechanistic basis for transvection is not known. As part of a genetic analysis of transvection, a study is being made of a class of mutation defined as modifiers of the eye color resulting from the interaction of zeste and white. This report details the observations that several of these mutations also have homeotic effects.

Key words

Zeste Suppressors Homeosis Polycomb group Transvection 


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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • C.-ting Wu
    • 1
    • 2
    • 3
  • Richard S. Jones
    • 3
  • Paul F. Lasko
    • 4
    • 5
  • William M. Gelbart
    • 3
  1. 1.SNSCheshireUSA
  2. 2.Department of BiologyYale UniversityNew HavenUSA
  3. 3.Department of Cellular and Developmental Biology, The Biological LaboratoriesHarvard UniversityCambridgeUSA
  4. 4.Department of Molecular BiologyMassachusetts General HospitalBostonUSA
  5. 5.Department of GeneticsHarvard Medical SchoolUSA

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