Molecular and General Genetics MGG

, Volume 204, Issue 3, pp 430–434

Sulfonylurea-resistant mutants of Arabidopsis thaliana

  • George W. Haughn
  • Chris Somerville

DOI: 10.1007/BF00331020

Cite this article as:
Haughn, G.W. & Somerville, C. Molec Gen Genet (1986) 204: 430. doi:10.1007/BF00331020


Chlorsulfuron-resistant mutants of Arabidopsis thaliana were isolated by screening for growth of seedlings in the presence of the herbicide. Both whole plants and derived tissue cultures were resistant to concentrations of the herbicide approximately 300-fold higher than that required to prevent growth of the wild-type. The resistance is due to a single dominant nuclear mutation at a locus designated csr which has been genetically mapped to chromosome-3. Acetohydroxy acid synthase activity in extracts from chlorsulfuron-resistant plants was much less-susceptible to inhibition by chlorsulfuron and a structurally related inhibitor than the activity in wild-type extracts. This suggests that the csr locus is the structural gene for acetohydroxy acid synthase.

Key words

Herbicide resistance Acetolactate synthase Acetohydroxy acid synthase Chlorsulfuron Sulfometuron methyl Imidazolinone 

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • George W. Haughn
    • 1
  • Chris Somerville
    • 1
  1. 1.MSU-DOE Plant Research LaboratoryMichigan State UniversityEast LansingUSA

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