Current Genetics

, Volume 21, Issue 2, pp 109–116

A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast

  • Michael A. White
  • Peter Detloff
  • Micheline Strand
  • Thomas D. Petes
Original Articles

Summary

Several investigators have reported that transcription stimulates some types of mitotic recombination in the yeast Saccharomyces cerevisiae. We find that mutations that reduce the rate of trancription of the yeast HIS4 gene in vegetative cells reduce the frequency of mitotic, but not meiotic, recombination events.

Key words

Transcription Recombination Yeast Gene conversion 

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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Michael A. White
    • 1
  • Peter Detloff
    • 1
    • 2
  • Micheline Strand
    • 3
  • Thomas D. Petes
    • 1
    • 3
  1. 1.Department of BiologyUniversity of North CarolinaChapel HillUSA
  2. 2.Department of Molecular Genetics and Cell BiologyUniversity of ChicagoChicagoUSA
  3. 3.Curriculum in GeneticsUniversity of North CarolinaChapel HillUSA

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