Child's Nervous System

, Volume 6, Issue 5, pp 250–253 | Cite as

Cerebral blood-flow velocity patterns in post-hemorrhagic ventricular dilation

  • K. Lui
  • J. Hellmann
  • A. Sprigg
  • A. Daneman
Original Papers


To evaluate the effect of ventricular dilation (VD) on cerebral hemodynamics, serial cerebral blood-flow velocity patterns from the anterior and middle cerebral, and circle of Willis arteries were examined by rangegated, pulsed Doppler sonography in premature infants developing post-hemorrhagic VD. Nine infants (25 to 30 weeks gestation) without a patent ductus arteriosus were studied until resolution of VD. Forty-nine cranial sonograms from all nine infants were reviewed independently and grouped cross-sectionally into mild, moderate and severe VD prior to shunt. The corresponding pulsatility index (PI) showed a consistent trend of increase with VD in all three studied vessels. In six infants, absent or reversed diastolic flow was observed at the height of VD. Four of these infants required V-P shunt. Immediate fall in PI occurred in all three vessels. Serial measurement of PI during VD reflects global changes in cerebrovascular resistance. Results confirmed PI could be a useful index in monitoring cerebral hemodynamic changes.

Key words

Cerebral blood flow Velocity patterns Post-hemorrhagic ventricular dilation Premature infants 


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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • K. Lui
    • 1
  • J. Hellmann
    • 1
  • A. Sprigg
    • 2
  • A. Daneman
    • 2
  1. 1.Department of PediatricsThe Hospital for Sick ChildrenTorontoCanada
  2. 2.Department of RadiologyThe Hospital for Sick ChildrenTorontoCanada

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