Innervation of the liver in guinea pig and rat
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In the guinea pig, a rich innervation is found in the trias as well as in the parenchyma. Many nerves traverse the entire liver lobules and may end near the central vein. The guinea pig hepatocyte innervation seems to be uniformly adrenergic. Electron microscopy shows that the varicosities of these nerves mostly form close contacts to the hepatocytes but also to other hepatic intralobular cells.
In the rat, the liver nerves are as a rule restricted to the triads, running mainly with smooth muscle containing blood vessels. It rarely happens that nerves penetrate into the lobule and come into contact with the peripherally located hepatocytes.
Key wordsLiver Innervation Adrenergic nerves Guinea pig Rat
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