Child's Nervous System

, Volume 9, Issue 1, pp 7–9 | Cite as

Supratentorial glioblastoma in children: a series of 27 surgically treated cases

  • Marco Artico
  • Luigi Cervoni
  • Paolo Celli
  • Maurizio Salvati
  • Lucio Palma
Original Papers


Reporting a series of 27 supratentorial glioblastomas in pediatric patients treated surgically in the Department of Neurosurgical Sciences-Neurosurgery Section—of “La Sapienza” University of Rome, we discuss the principal clinical features, treatment and prognosis of the tumour with reference to the salient published series.

Key words

Glioblastoma Children Monstrocellular glioblastoma 


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  1. 1.
    Burger PC, Vollmer RT (1980) Histologic factors of prognosis significance in the glioblastoma multiforme. Cancer 46:1179–1186Google Scholar
  2. 2.
    Busch E, Christensen E (1947) The three types of glioblastoma. J Neurosurg 4: 200–220Google Scholar
  3. 3.
    Davis L, Martin J, Goldstein SL, Ashkenazy M (1949) A study of 211 patients with verified glioblastoma multiforme. J Neurosurg 6:33–44Google Scholar
  4. 4.
    Dohrmann GJ, Farwell JR, Flannery J (1976) Glioblastoma multiforme in children. J Neurosurg 44:442–448Google Scholar
  5. 5.
    Dropcho EJ, Wisoff JH, Walker RW, Allen JC (1987) Supratentorial malignant gliomas in childhood: a review of fifty cases. Ann Neurol 22:355–364Google Scholar
  6. 6.
    Hollerhage HG, Zumkeller M, Becker M, Dietz H (1991) Influence of type and extent of surgery on early results and survival time in glioblastoma multiforme. Acta Neurochir (Wien) 113:31–37Google Scholar
  7. 7.
    Jacquet G, Godard J, Carbillet C, Steimle R (1989) Glioblastome du cervelet chez un enfant. A propos d'un cas revue de la litterature. Neurochirurgie 35:64–69Google Scholar
  8. 8.
    Jelsma R, Bucy PC (1969) Glioblastoma multiforme: its treatment and some factors affecting survival. Arch Neurol 20:161–171Google Scholar
  9. 9.
    Koos WT, Miller MH (1971) Intracranial tumours of infants and children. Thieme, StuttgartGoogle Scholar
  10. 10.
    Matsukado Y, MacCarty CS, Kernohan JW (1961) The growth of glioblastoma multiforme (astrocytoma grades 3 and 4) in neurosurgical practice. J Neurosurg 18:636–644Google Scholar
  11. 11.
    Netsky MG, August B, Fowler W (1950) The longevity of patients with glioblastoma multiforme. J Neurosurg 7:261–269Google Scholar
  12. 12.
    Palma L, Di Lorenzo N, Guidetti B (1978) Lymphocytic infiltrates trates in primary glioblastoma and recidivous gliomas. Incidence, fate, and relevance to prognosis in 228 operated cases. J Neurosurg 49:854–861Google Scholar
  13. 13.
    Palma L, Celli P, Maleci A, Di Lorenzo N, Cantore C (1989) Malignant monstrocellular brain tumour. A study of 42 surgically treated cases. Acta Neurochir (Wien) 97:17–25Google Scholar
  14. 14.
    Pedersen H, Cjerris F, Klinken L (1989) Malignancy criteria in computed tomography of primary supratentorial tumors in infancy and childhood. Neuroradiology 31:24–28Google Scholar
  15. 15.
    Phuphanich S, Edwards MSB, Levin VA, Vestnys PS, Wara WM, Davis RL, Wilson CB (1984) Supratentorial malignant gliomas of childhood. Result of treatment with radiation therapy and chemotherapy. J Neurosurg 60: 495–499Google Scholar
  16. 16.
    Wakai S, Arai T, Nagai M (1984) Congenital brain tumors. Surg Neurol 21:597–609Google Scholar

Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Marco Artico
    • 1
  • Luigi Cervoni
    • 2
  • Paolo Celli
    • 2
  • Maurizio Salvati
    • 2
  • Lucio Palma
    • 3
  1. 1.Department of Human Anatomy, Faculty of Pharmacology“La Sapienza” UniversityRomeItaly
  2. 2.Department of Neurosurgical Sciences, Neurosurgery Section“La Sapienza” UniversityRomeItaly
  3. 3.Department of NeurosurgeryUniversity of SienaSienaItaly

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