Urological Research

, Volume 19, Issue 5, pp 277–280

Single potential analysis of cavernous electrical activity

  • C. G. Stief
  • W. F. Thon
  • M. Djamilian
  • W. de Riese
  • K. W. Fritz
  • E. P. Allhoff
  • U. Jonas
Article

Summary

Recording of cavernous electric activity was performed in 178 patients with erectile dysfunction and in 37 normal patients. In 34/37 normal patients, potentials of a uniform shape were recorded during flaccidity: At cut-off frequences of 0.5–500 Hz, the length was 8–18 (mean 12.8, SD 2.8), the amplitude 250–750 (mean 444, SD 109) μV, and the polyphasity 8–22 (mean 13.8, SD 3.3). In impotent patients with upper motor neuron lesions or peripheral lesions, specific types of potentials were observed. In 11/14 impotent patients with insulin-dependent diabetes for over 20 years and clinical findings of cavernous myopathy, potentials showed low amplitude, irregular shape, and slow depolarizations. In 51% of the consecutive impotent patients, abnormal findings of cavernous electric activity were recorded. Our clinical study suggests that single potential analysis of cavernous electric activity (SPACE) may be useful in the diagnosis of cavernous autonomic neuropathy and cavernous smooth muscle myopathy.

Key words

Erectile dysfunction Autonomic innervation Cavernous electric activity Diagnosis of autonomic dysfunction 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Brindley GS (1983) Cavernosal alpha-blockade: a new technique for investigating and treating erectile impotence. Br J Psychiatry 143:332Google Scholar
  2. 2.
    Ellenberg M (1980) Development of urinary bladder dysfunction in diabetes mellitus. Ann Intern Med 92:321–324Google Scholar
  3. 3.
    Ertekin C, Ertekin N, Almis S (1989) Autonomic sympathetic nerve involvement in diabetic impotence. Neurourol Urodyn 8:589Google Scholar
  4. 4.
    Gerstenberg TC, Nordling J, Hald H, Wagner G (1989) Standardized evaluation of erectile dysfunction in 95 consecutive patients. J Urol 141:857Google Scholar
  5. 5.
    Jevtich MJ (1983) Non-invasive vascular and neurogenic tests in use for evaluation of angiogenic impotence. Inter Angio 3:964Google Scholar
  6. 6.
    Laivas JG, Zayed AA, Labib KB (1981) The bulbocavernous reflex in urology. J Urol 126:197Google Scholar
  7. 7.
    Lavoisier P, Proulx J, Courtois F, Carful F (1989) Bulbocavernous reflex. J Urol 141:311Google Scholar
  8. 8.
    Lue TF, Takamura T, Schmidt RA, Tanagho EA (1983) Hemodynamics of erection in the monkey. J Urol 130:1237Google Scholar
  9. 9.
    Lue TF, Hricak H, Marich KW, Tanagho ET (1985) Evaluation of arteriogenic impotence with intracorporal injection of papaverine and the duplex ultrasound scanner. Semin Urol 3:43Google Scholar
  10. 10.
    Lue TF, Hricak H, Schmidt RA, Tanagho EA (1986) Functional evaluation of penile veins by cavernosography in papaverineinduced erection. J Urol 135:479Google Scholar
  11. 11.
    Persson C, Diederichs W, Lue TF, Ven TS, Fishman I, Lin PH, Tanagho ET (1989) Correlation of altered ultrastructure with clinical arterial evaluation. J Urol 142:1462Google Scholar
  12. 12.
    Siroky MB, Sax DS, Krane RJ (1979) Sacral signal tracing. J Urol 122:661Google Scholar
  13. 13.
    Stief CG, Bähren W Gall H, Scherb W (1988) Functional evaluation of penile hemodynamics. J Urol 139:734Google Scholar
  14. 14.
    Tejada de S, Goldstein I, Krane RJ (1988) Local control of penile erection. Urol Clin N Am 15:9Google Scholar
  15. 15.
    Wagner G (1976) Contractility of myometrial transplants. In: Coutinhu EM, Fuchs F (eds) Physiology and genetics of reproduction, part B. Plenum, New YorkGoogle Scholar
  16. 16.
    Wagner G, Gerstenberg T (1988) Human in vivo studies of electrical activity of corpus cavernosum. J Urol 139:327AGoogle Scholar
  17. 17.
    Wagner G, Gerstenberg T, Levin RJ (1989) Electrical activity of corpus cavernosum during flaccidity and erection of the human penis. J Urol 42:723Google Scholar
  18. 18.
    Wetterauer U, Stief CG, Kulvelis F, Staubesand J, Sommerkamp H (1990) The electron microscopic ultrastructure of cavernous tissue in erectile dysfunction. J Urol 143:509AGoogle Scholar
  19. 19.
    Virag R (1982) Intracavernous injection of papaverine for erectile failure. Letter to the editor. Lancet II:938Google Scholar
  20. 20.
    Zorgniotti AW, Lefleur RS (1985) Auto-injection of the corpus cavernosum with a vasoactive drug combination for vasculogenic impotence. J Urol 133:39Google Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • C. G. Stief
    • 1
  • W. F. Thon
    • 1
  • M. Djamilian
    • 1
  • W. de Riese
    • 1
  • K. W. Fritz
    • 1
  • E. P. Allhoff
    • 1
  • U. Jonas
    • 1
  1. 1.Department of Urology and AnesthesiologyUniversity ClinicHannoverGermany

Personalised recommendations