Chromosoma

, Volume 58, Issue 1, pp 51–61 | Cite as

Sequence of DNA replication in 277 R- and Q-bands of human chromosomes using a BrdU treatment

  • B. Dutrillaux
  • J. Couturier
  • Claude-Lise Richer
  • Evani Viegas-Péquignot
Article

Abstract

Replication times for all important chromosome bands, of both types R and Q (277 structures) are analysed. — The R-bands form a group of structures whose DNA replicates during the early S-phase, while the DNA situated in the Q-bands replicates during the late S-phase. — There may not exist overlapping between replication times of these two types of structures. — The widest R-bands are those which are the earliest to replicate; in general, the most intense Q-bands are those which are the latest to replicate. Especially among these last ones, a certain asynchronism exists between the replication times. Finally the heterochromatin of chromosomes 1, 16 and Y and of the short arms of the acrocentrics could contain two types of DNA which replicate at different times.

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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • B. Dutrillaux
    • 1
  • J. Couturier
    • 1
  • Claude-Lise Richer
    • 2
  • Evani Viegas-Péquignot
    • 1
  1. 1.Institut de Progenèse (Pr. J. Lejeune)ParisFrance
  2. 2.Département d'AnatomieUniversité de MontréalCanada

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