Human red cell acid phosphatase polymorphism
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Red cell acid phosphatase phenotypes were determined in 401 unrelated persons from Southwestern Germany. The frequencies of genes Pa, Pb and Pc were estimated to be p=0.328, q=0.630 and r=0.042.
Experiences in 101 cases of disputed paternity with 151 men involved are reported. 22 men could be excluded from paternity on the basis of red cell acid phosphatase phenotypes.
In all 140 mother-child-combinations tested the distribution of red cell acid phosphatase variants was compatible with the genetic model suggested by Hopkinson et al.
Usefulness of the system in forensic cases of disputed paternity is discussed.
KeywordsInternal Medicine Metabolic Disease Acid Phosphatase Genetic Model Forensic Case
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