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Archives of Toxicology

, Volume 62, Issue 6, pp 476–478 | Cite as

Possible involvement of nuclei in cadmium-induced modifications of cultured cells

  • Maria Albertina Fighetti
  • Maddalena Miele
  • A. Montella
  • Maria Speranza Desole
  • A. M. Congiu
  • V. Anania
Short Communication

Abstract

Reduced metaphase number and shortening of metaphase chromosomes were detected in McCoy cells exposed to 100 μM CdS04 (maximal exposure time: 7 h). One hour exposure to 109Cd was enough to label the cell nucleus. This possibly suggests an early nuclear involvement in Cd-induced cell damage.

Key words

Cadmium Cytoskeleton Nuclei McCoy cells 

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References

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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • Maria Albertina Fighetti
    • 1
  • Maddalena Miele
    • 1
  • A. Montella
    • 2
  • Maria Speranza Desole
    • 1
  • A. M. Congiu
    • 3
  • V. Anania
    • 1
  1. 1.Institutes of PharmacologyUniversity of SassariSassariItaly
  2. 2.Human Anatomy (Faculty of Medicine)University of SassariSassariItaly
  3. 3.Chair of Pathology (Faculty of Mt, Ph. and Nt. Sciences)University of SassariSassariItaly

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