Human Genetics

, Volume 83, Issue 2, pp 194–196 | Cite as

The human homolog of the myeloproliferative virus maps to chromosome band 1p34

  • Maryvonne Le Coniat
  • Michèle Souyri
  • Isabelle Vigon
  • Françoise Wendling
  • Pierre Tambourin
  • Roland Berger
Short Communications

Summary

The human homologue of the recently isolated myeloproliferative leukemia virus, a retrovirus that induces myeloproliferative disorder in mouse, has been mapped in man to chromosome band 1p34 by in situ hybridization.

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References

  1. Caubet JF, Mathieu-Mahul D, Bernheim A, Larsen CJ, Berger R (1985) Human proto-oncogene c-mos maps to 9q11. EMBO J 4: 2245–2248Google Scholar
  2. Cook PJL, Hamerton JL (1979) Report of the committee on the genetic constitution of chromosome 1. (5th International Workshop on Human Gene Mapping). Cytogenet Cell Genet 25:9–20Google Scholar
  3. Dracopoli NC, Stanger BZ, Lager M, Housman DE (1988) Localization of the FGR protooncogene on the genetic linkage map of human chromosome 1p. Genomics 3:124–128Google Scholar
  4. Dubart A, Mattei MG, Raich N, Beaupain D, Romeo PH, Mattei JF, Gossens M (1986) Assignment of human uroporphyrinogen decarboxylase (URO-D) to the p34 band of chromosome 1. Hum Genet 73:277–279Google Scholar
  5. Feinberg AP, Vogelstein B (1983) A technique for radiolabelling DNA restriction endonuclease fragments to high specificity activity. Anal Biochem 132:6–13Google Scholar
  6. Fowler ML, Nakai H, Byers MG, Fukushima H, Eddy RL, Henry WM, Haley LL, O'Brien JS, Shows TB (1986) Chromosome 1 localization of the human alpha-l-fucosidase structural gene with a homologous site on chromosome 2. Cytogenet Cell Genet 43: 103–108Google Scholar
  7. Haluska FG, Huebner K, Isobe M, Nishimura T, Croce CM, Vogt PK (1988) Localization of the human JUN protooncogene to chromosome region 1p31–32. Proc Natl Acad Sci USA 85:2215–2218Google Scholar
  8. Harper ME, Saunders GF (1981) Localization of single copy DNA sequences on G-banded human chromosomes by in situ hybridization. Chromosoma 83:431–439Google Scholar
  9. Marth JD, Distèche C, Pravtecheva D, Ruddle F, Krebs EG, Perlmutter RM (1986) Localization of a lymphocyte-specific protein tyrosine kinase gene (LCK) at a site of frequent chromosomal abnormalities in human lymphomas. Proc Natl Acad Sci USA 83:7400–7404Google Scholar
  10. McBride OW, Kirsch I, Hollis G, Nau M, Battey J, Minna J (1985) Human l-myc (MYCL) proto-oncogene is on chromosome 1p32. Cytogenet Cell Genet 40:694Google Scholar
  11. Penciolelli JF, Wendling F, Robert-Lezenes J, Barque JF, Tambourin P, Gisselbrecht S (1987) Genetic analysis of myeloproliferative leukemia virus, a novel acute leukemogenic replication-defective retrovirus. J Virol 61:579–583Google Scholar
  12. Trent JM, Kaneko Y, Mitelman F (1988) Report on the committee on structural chromosome changes in neoplasia. (9.5th International Workshop on Human Gene Mapping) Cytogenet Cell Genet 49: 236–253Google Scholar
  13. Wendling F, Varlet P, Charon M, Tambourin P (1986) A retrovirus complex inducing an acute myeloproliferative leukemic disorder in adult mice. Virology 149:242–246Google Scholar
  14. Wendling F, Penciolelli M, Charon M, Tambourin P (1989) Factor-independent erythropoietic progenitor cells in leukemia induced by the myeloproliferative leukemia virus. Blood 73:1161–1167Google Scholar
  15. Yunis JJ, Sawyer JR, Ball DW (1978) Characterization of banding patterns of metaphase-prophase G-banded chromosomes and their use in gene mapping. Cytogenet Cell Genet 22:679–683Google Scholar

Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • Maryvonne Le Coniat
    • 1
    • 2
  • Michèle Souyri
    • 3
  • Isabelle Vigon
    • 3
  • Françoise Wendling
    • 3
  • Pierre Tambourin
    • 3
  • Roland Berger
    • 1
    • 2
  1. 1.Unité 301 INSERMHôpital Saint-LouisParisFrance
  2. 2.LOI CNRS-Centre G. HayemHôpital Saint-LouisParisFrance
  3. 3.Unité 152 INSERM-CHU Chochin-Port-RoyalParisFrance

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