Human Genetics

, Volume 65, Issue 2, pp 144–146

Methyl green is a substitute for distamycin A in the formation of distamycin A/DAPI C-bands

  • T. A. Donlon
  • R. E. Magenis
Original Investigations

Summary

The DA/DAPI technique has been found to be useful in the identification of specific chromosomal regions on human chromosomes. The realization that distamycin A (DA) is no longer commercially available has necessitated the development of an alternative technique. We describe a technique, MG/DAPI, which substitutes the AT-specific dye methyl green for distamycin A and gives results identical to those of the DA/DAPI technique.

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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • T. A. Donlon
    • 1
  • R. E. Magenis
    • 1
  1. 1.Department of Medical Genetics and the Child Development and Rehabilitation CenterOregon Health Sciences UniversityPortlandUSA

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