Water, Air, and Soil Pollution

, Volume 24, Issue 2, pp 189–206 | Cite as

A comprehensive study of risk assessment for a hazardous compound of public health concern

  • T. P. Halappa Gowda
  • John D. Lock
  • Ruth G. Kurtz


A comprehensive approach to risk assessment was developed by coupling an environmental fate model to the available health effects data. This approach was used to determine the risk due to an emission of 100 Mg L−1 of 2,4,6-trichlorophenol (2.4.6-TCP) to a water body similar to Hamilton Harbour. The results indicated that a reduction in emissions to the harbour from 100 to 27.6 fig L−1 would be required if a risk level of 1 in 106 is closen.


Public Health Water Body Risk Assessment Health Effect Health Concern 
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  1. Ames, B. N., McCann, J., and Yamasaki, E.: 1975. Test. Muta. Res. 31, 347.Google Scholar
  2. Arrhenius, E., Renberg, L., Johansson, L., and Zetterquist, M.: 1977. Chem. Bio. Interact. 18, 35.Google Scholar
  3. Bhatnagar, R. S., Hussain, M. Z., and Belton, J. C.: 1979, in S. D. Lee and J. B. Mudd (eds.), Assessing Toxic Effects of Environmental Pollutants, Ann Arbor Science, Ann Arbor, Michigan, pp. 121–150.Google Scholar
  4. Bjerke, E. L., Herman, J. L., Miller, P. W., and Wetters, J. H.: 1972, Jour. Agric. Food Chem. 20, 963.Google Scholar
  5. Burttschell, R. H., Rosen, A. A., Middleton, F. M., and Ettinger M. B.: 1959, J.A. W.W.A. 5, 205.Google Scholar
  6. Bysshe, S. E.: 1982, in Lyman et al. (eds.), Handbook of Chemical Property Estimation Methods —Environmental Behaviour of Organic Compounds, McGraw-Hill Book Company, Toronto.Google Scholar
  7. Chapman, P. M., Romberg, G. P., and Vigers, G. A.: 1982, J. Water Pollution Control Federation 54, 292.Google Scholar
  8. Clark, D. E., Palmer, J. S., Radeleff, R. D., Crookshank, H. R., and Farr, F. M.: 1976, Jour. Agric. Food Chem. 23, 573.Google Scholar
  9. Conway, R. A. (ed.): 1982, Environmental Risk Analysis for Chemicals, Van Nostrand Reinhold Company Ltd.Google Scholar
  10. Fahrig, R., Nilsson, C. A., and Rappe, C.: 1978, in K. R. Rao, (ed.), Pentachlorophenol: Chemistry, Pharmacology and Environmental Toxicology, Plenum Press, New York.Google Scholar
  11. Farquharson, M. E., Gage, J. C., and Northover, J.: 1958, Br. Jour. Pharmacol. 13, 20.Google Scholar
  12. Foster, T. S. and Saha, J. G.: 1978, Jour. Environ. Sci. Health 13, 25.Google Scholar
  13. Gaylor, D. W. and Shapiro, R. E.: 1979, in M. A. Mehlman et al. (eds.), Advances in Modern Toxicology, Vol. 1, part 2, Hemisphere Publishing Corp., Washington, D.C., pp. 65–87.Google Scholar
  14. Handy, R. and Schindler, A.: 1976, Estimation of Permissible Concentrations of Pollutants for Continuous Exposure, EPA 600/2–76–155, Environmental Protection Agency, Washington, D.C., p. 61.Google Scholar
  15. Harris, G. P.: 1976, Biological Study of Hamilton Harbour - 1975. Technical Report Series No. l, Dept. of Biology, McMaster University, Hamilton, Ontario, Canada.Google Scholar
  16. Hoak,: 1956, quoted in: ‘Water Quality Criteria for European Freshwater Fish’, by the European Inland Fisheries Advisory Commission (a subcommittee of the FAO-Food and Agriculture Organization of the United Nations), Water Research 7, 929 (1973).Google Scholar
  17. Ismail, R., Hockwin, O., Korte, and Klein, W.: 1975, Exp. Eye Res. 20, 1979.Google Scholar
  18. Kohli, J., Jones, D., and Safe, S.: 1976, Can. Jour. Biochem. 54, 203.Google Scholar
  19. Kohli, B. K.: 1979, J. Great Lakes Res. 5, 36–44.Google Scholar
  20. Korte, F., Freitag, D., Geyer, H., Klein, W. Kraus, A. G. and Lahaniatis, E.: 1978, Chemosphere 7, 79.Google Scholar
  21. Kutz, F. W., Murphy, R. S., and Strassman, S. C.: 1978, in K. R. Rao (ed.), Pentachlorophenol; Chemistry, Pharmacology and Environmental Toxicology, Plenum Press, New York p. 363.Google Scholar
  22. Lyman, W. J., Reehl, W. F., and Rosenblatt, D. H.: 1982, Handbook of Chemical Property Estimation Methods-Environmental Behavior of Organic Compounds, McGraw-Hill Book Co., Toronto.Google Scholar
  23. Mackay, D.: 1979, Env. Sci. and Techn. 13, 1218.Google Scholar
  24. Mackay, D. and Paterson, S.: 1981. Env. Sci. & Tech. 15, 1006.Google Scholar
  25. Mackay, D. and Paterson, S.: 1982, Env. Sci. & Tech. 16, 654A.Google Scholar
  26. Maugh, T. H. II.: 1978, Science 202, 37.Google Scholar
  27. Ministry of the Environment (MOE): 1978, Water Management-Goals, Policies, Objectives and Implementation Procedures of the Ministry of the Environment, Water Resources Branch, Ontario Ministry of the Environment, Toronto, Canada.Google Scholar
  28. Mitsuda, H., Murakami, K., and Kawai, F.: 1963, Agric. Biol. Chem. 27, 366.Google Scholar
  29. Moza, P., Mostafa, I., and Klein, W.: 1974, Chemosphere 3, 255.Google Scholar
  30. National Academy Press (NAP): 1982, Drinking Water and Health, Vol. 4, National Academy Press, Washington, D.C.Google Scholar
  31. National Academy of Sciences (NAS): 1977. Drinking Water and Health, Vol. 1, National Academy of Sciences, Washington, D.C.Google Scholar
  32. National Cancer Institute (NCI): 1979,1979 Bioassay of 2,4,6-Trichlorophenol for Possible Carcinogenicity. US Public Health Service, NIH, US Department of Health, Education and Welfare (Technical Service Report Ser. No. 155).Google Scholar
  33. National Institute of Occupational Safety and Health (NIOSH): 1974, Toxic Substances List, U.S. National Institute of Occupational Safety and Health.Google Scholar
  34. Rasanen, L., Hattula, M. L., and Arstila, A. U.: 1977, Bull. Environ. Contam. Toxicol. 18, 565.Google Scholar
  35. Roberts, M. S., Anderson, R. A., and Swarbick, J.: 1977, Jour. Pharm. Pharmac. 29, 677.Google Scholar
  36. Rosenblatt, D. H., Dacre, J. C., and Cogley, D. R.: 1982, in Conway, R. A. (ed.), Environmental Risk Analysis for Chemicals, Van Nostrand Reinhold Co., Toronto, 474.Google Scholar
  37. Stannard, D. J. and Scotter, A.: 1977, New Zea. Jour. Diary Sci. Technol. 12, 140.Google Scholar
  38. Stockdale, M. and Selwyn, M. J.: 1971, Eur. Jour. Biochem. 21, 416.Google Scholar
  39. Tanaka, K., Kurihara, N., and Nakajima, M.: 1977, Agric. Biol. Chem. 41, 733.Google Scholar
  40. United States Environmental Protection Agency (USEPA): 1976, Quality Criteria for Water, U.S. Environmental Protection Agency, Washington, D.C.Google Scholar
  41. United States Environmental Protection Agency (USEPA): 1979a, Water Quality Criteria, Request for Comments, U.S. Federal Register 44, 15926-981.Google Scholar
  42. United States Environmental Protection Agency (USEPA): 1979b, Water Quality Criteria; Availability, U.S. Federal Register 44, 43660-697.Google Scholar
  43. U.S. Environmental Protection Agency (USEPA): 1980, Ambient Water Quality Criteria for Chlorinated Phenols, (Document No. 440/5-80-032).Google Scholar
  44. Verscheuren, K.: 1977. Handbook of Environmental Data on Organic Chemicals, Van Nostrand-Reinhold Co., Toronto.Google Scholar

Copyright information

© D. Reidel Publishing Company 1985

Authors and Affiliations

  • T. P. Halappa Gowda
    • 1
  • John D. Lock
    • 1
  • Ruth G. Kurtz
    • 1
  1. 1.Water Resources DivisionGore & Storrie LimitedTorontoCanada

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