Human Genetics

, Volume 71, Issue 2, pp 150–154 | Cite as

A 45,X male with evidence of a translocation of Y euchromatin onto chromosome 15

  • W. Schempp
  • B. Weber
  • A. Serra
  • G. Neri
  • A. Gal
  • U. Wolf
Original Investigations
Received:
Revised:

Summary

A 19-year-old male with azoospermia was found to have a 45,X karyotype with additional euchromatic material on 15p. The parents' karyotypes are normal. The cytogenetic data, the positive H-Y-typing, and the presence of Yp-specific restriction fragments detected in the proband's genome by molecular DNA probes suggest that the short arm of the Y chromosome, including part of the centromere, is translocated onto the nucleolus organizer region (NOR) of chromosome 15.

Keywords

Internal Medicine Metabolic Disease Restriction Fragment Organizer Region Nucleolus Organizer Region 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • W. Schempp
    • 1
  • B. Weber
    • 1
  • A. Serra
    • 2
  • G. Neri
    • 2
  • A. Gal
    • 1
    • 3
  • U. Wolf
    • 1
  1. 1.Institut für Humangenetik und Anthropologie der Universität FreiburgFreiburg i. Br.Federal Republic of Germany
  2. 2.Istituto di Genetica Umana, Fac. Med. “A. Gemelli”, UCSCRomaItaly
  3. 3.Institut für Humangenetik der Universität BonnBonnFederal Republic of Germany

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